TY - JOUR AU - Zhu, N. AU - Zhang, D. AU - Wang, W. AU - Li, X. AU - Yang, B. AU - Song, J. PY - 2020 DA - 2020// TI - A novel coronavirus from patients with pneumonia in China, 2019 JO - N Engl J Med VL - 382 UR - https://doi.org/10.1056/NEJMoa2001017 DO - 10.1056/NEJMoa2001017 ID - Zhu2020 ER - TY - JOUR AU - Dobson, J. AU - Whitley, R. J. AU - Pocock, S. AU - Monto, A. S. PY - 2015 DA - 2015// TI - Oseltamivir treatment for influenza in adults: a meta-analysis of randomised controlled trials JO - Lancet. VL - 385 UR - https://doi.org/10.1016/S0140-6736(14)62449-1 DO - 10.1016/S0140-6736(14)62449-1 ID - Dobson2015 ER - TY - JOUR AU - Lipsitch, M. AU - Riley, S. AU - Cauchemez, S. AU - Ghani, A. C. AU - Ferguson, N. M. PY - 2009 DA - 2009// TI - Managing and reducing uncertainty in an emerging influenza pandemic JO - N Engl J Med VL - 361 UR - https://doi.org/10.1056/NEJMp0904380 DO - 10.1056/NEJMp0904380 ID - Lipsitch2009 ER - TY - JOUR AU - Wang, X. L. AU - Wong, C. M. AU - Chan, K. H. AU - Chan, K. P. AU - Cao, P. H. AU - Peiris, J. M. PY - 2014 DA - 2014// TI - Hospitalization risk of the 2009 H1N1 pandemic cases in Hong Kong JO - BMC Infect Dis VL - 14 UR - https://doi.org/10.1186/1471-2334-14-32 DO - 10.1186/1471-2334-14-32 ID - Wang2014 ER - TY - JOUR AU - Ouzzani, M. AU - Hammady, H. AU - Fedorowicz, Z. AU - Elmagarmid, A. PY - 2016 DA - 2016// TI - Rayyan-a web and mobile app for systematic reviews JO - Syst Rev VL - 5 UR - https://doi.org/10.1186/s13643-016-0384-4 DO - 10.1186/s13643-016-0384-4 ID - Ouzzani2016 ER - TY - JOUR AU - Hung, I. F. AU - Lee, C. K. AU - Lee, K. L. AU - Yan, W. W. AU - Chan, K. PY - 2013 DA - 2013// TI - Hyperimmune IV immunoglobulin treatment: a multicenter double-blind randomized controlled trial for patients with severe 2009 influenza A(H1N1) infection JO - Chest. VL - 144 UR - https://doi.org/10.1378/chest.12-2907 DO - 10.1378/chest.12-2907 ID - Hung2013 ER - TY - JOUR AU - Wang, C. H. AU - Chung, F. T. AU - Lin, S. M. AU - Huang, S. Y. AU - Chou, C. L. AU - Lee, K. Y. PY - 2014 DA - 2014// TI - Adjuvant treatment with a mammalian target of rapamycin inhibitor, sirolimus, and steroids improves outcomes in patients with severe H1N1 pneumonia and acute respiratory failure JO - Crit Care Med VL - 42 UR - https://doi.org/10.1097/CCM.0b013e3182a2727d DO - 10.1097/CCM.0b013e3182a2727d ID - Wang2014 ER - TY - JOUR PY - 2013 DA - 2013// TI - Effect of double dose oseltamivir on clinical and virological outcomes in children and adults admitted to hospital with severe influenza: double blind randomised controlled trial JO - BMJ VL - 346 UR - https://doi.org/10.1136/bmj.f3039 DO - 10.1136/bmj.f3039 ID - ref8 ER - TY - JOUR AU - Kimberlin, D. W. AU - Acosta, E. P. AU - Prichard, M. N. AU - Sanchez, P. J. AU - Ampofo, K. AU - Lang, D. PY - 2013 DA - 2013// TI - Oseltamivir pharmacokinetics, dosing, and resistance among children aged <2 years with influenza JO - J Infect Dis VL - 207 UR - https://doi.org/10.1093/infdis/jis765 DO - 10.1093/infdis/jis765 ID - Kimberlin2013 ER - TY - JOUR AU - Ison, M. G. AU - Fraiz, J. AU - Heller, B. AU - Jauregui, L. AU - Mills, G. AU - O’Riordan, W. PY - 2014 DA - 2014// TI - Intravenous peramivir for treatment of influenza in hospitalized patients JO - Antivir Ther VL - 19 UR - https://doi.org/10.3851/IMP2680 DO - 10.3851/IMP2680 ID - Ison2014 ER - TY - JOUR AU - Marty, F. M. AU - Man, C. Y. AU - Horst, C. AU - Francois, B. AU - Garot, D. AU - Manez, R. PY - 2014 DA - 2014// TI - Safety and pharmacokinetics of intravenous zanamivir treatment in hospitalized adults with influenza: an open-label, multicenter, single-arm, phase II study JO - J Infect Dis VL - 209 UR - https://doi.org/10.1093/infdis/jit467 DO - 10.1093/infdis/jit467 ID - Marty2014 ER - TY - JOUR AU - Lee, N. AU - Hui, D. S. AU - Zuo, Z. AU - Ngai, K. L. AU - Lui, G. C. AU - Wo, S. K. PY - 2013 DA - 2013// TI - A prospective intervention study on higher-dose oseltamivir treatment in adults hospitalized with influenza a and B infections JO - Clin Infect Dis VL - 57 UR - https://doi.org/10.1093/cid/cit597 DO - 10.1093/cid/cit597 ID - Lee2013 ER - TY - JOUR AU - Rojek, A. M. AU - Horby, P. W. PY - 2016 DA - 2016// TI - Modernising epidemic science: enabling patient-centred research during epidemics JO - BMC Med VL - 14 UR - https://doi.org/10.1186/s12916-016-0760-x DO - 10.1186/s12916-016-0760-x ID - Rojek2016 ER - TY - JOUR AU - Tran, T. H. AU - Ruiz-Palacios, G. M. AU - Hayden, F. G. AU - Farrar, J. PY - 2009 DA - 2009// TI - Patient-oriented pandemic influenza research JO - Lancet. VL - 373 UR - https://doi.org/10.1016/S0140-6736(09)61131-4 DO - 10.1016/S0140-6736(09)61131-4 ID - Tran2009 ER - TY - JOUR AU - Hayden, F. G. AU - Farrar, J. AU - Peiris, J. S. PY - 2014 DA - 2014// TI - Towards improving clinical management of Middle East respiratory syndrome coronavirus infection JO - Lancet Infect Dis VL - 14 UR - https://doi.org/10.1016/S1473-3099(14)70793-5 DO - 10.1016/S1473-3099(14)70793-5 ID - Hayden2014 ER - TY - STD TI - Grein J, Ohmagari N, Shin D, Diaz G, Asperges E, Castagna A, et al. Compassionate use of remdesivir for patients with severe Covid-19. New England J Med. 2020; [Epub ahead of print]. ID - ref16 ER - TY - STD TI - Gautret P, Lagier JC, Parola P, Hoang VT, Meddeb L, Mailhe M, et al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial. Int J Antimicrob Agents. 2020;105949 [Epub ahead of print]. ID - ref17 ER - TY - STD TI - Rojek AM, Horby PW. Offering patients more: how the West Africa Ebola outbreak can shape innovation in therapeutic research for emerging and epidemic infections. Philos Trans R Soc Lond B Biol Sci. 2017;372(1721). ID - ref18 ER - TY - JOUR AU - Woodcock, J. AU - LaVange, L. M. PY - 2017 DA - 2017// TI - Master protocols to study multiple therapies, multiple diseases, or both JO - N Engl J Med VL - 377 UR - https://doi.org/10.1056/NEJMra1510062 DO - 10.1056/NEJMra1510062 ID - Woodcock2017 ER - TY - STD TI - Group RC, Horby P, Lim WS, Emberson JR, Mafham M, Bell JL, et al. Dexamethasone in hospitalized patients with Covid-19 - preliminary report. N Engl J Med. 2020. ID - ref20 ER - TY - STD TI - The National Academies Press. Integrating clinical research into epidemic response: the Ebola experience. Washington, DC: The National Academies of Sciences, Engineering, Medicine; 2017. ID - ref21 ER - TY - JOUR AU - Rishu, A. H. AU - Marinoff, N. AU - Julien, L. AU - Dumitrascu, M. AU - Marten, N. AU - Eggertson, S. PY - 2017 DA - 2017// TI - Time required to initiate outbreak and pandemic observational research JO - J Crit Care VL - 40 UR - https://doi.org/10.1016/j.jcrc.2017.02.009 DO - 10.1016/j.jcrc.2017.02.009 ID - Rishu2017 ER - TY - JOUR AU - Rojek, A. M. AU - Dunning, J. AU - Leliogdowicz, A. AU - Castle, L. AU - Lieshout, M. AU - Carson, G. PY - 2018 DA - 2018// TI - Regulatory and operational complexities of conducting a clinical treatment trial during an Ebola virus disease epidemic JO - Clin Infect Dis VL - 66 UR - https://doi.org/10.1093/cid/cix1061 DO - 10.1093/cid/cix1061 ID - Rojek2018 ER - TY - STD TI - Wellcome Trust and The Academy of Medical Sciences. Use of neuraminidase inhibitors in influenza 2015. Available from: https://acmedsci.ac.uk/file-download/38069-561595082cd83.pdf. Accessed 29 Apr 2020. UR - https://acmedsci.ac.uk/file-download/38069-561595082cd83.pdf ID - ref24 ER - TY - JOUR AU - Dunning, J. AU - Kennedy, S. B. AU - Antierens, A. AU - Whitehead, J. AU - Ciglenecki, I. AU - Carson, G. PY - 2016 DA - 2016// TI - Experimental treatment of Ebola virus disease with brincidofovir JO - PLoS One VL - 11 UR - https://doi.org/10.1371/journal.pone.0162199 DO - 10.1371/journal.pone.0162199 ID - Dunning2016 ER - TY - JOUR AU - Cheng, V. C. AU - Chan, J. F. AU - Yuen, K. Y. PY - 2013 DA - 2013// TI - Clinical management and infection control of SARS: lessons learned JO - Antivir Res VL - 100 UR - https://doi.org/10.1016/j.antiviral.2013.08.016 DO - 10.1016/j.antiviral.2013.08.016 ID - Cheng2013 ER - TY - JOUR AU - Kayem, N. D. AU - Rojek, A. AU - Denis, E. AU - Salam, A. AU - Reis, A. AU - Olliaro, P. PY - 2019 DA - 2019// TI - Clinical REsearch during outbreaks (CREDO) training for low- and middle-income countries JO - Emerg Infect Dis VL - 25 UR - https://doi.org/10.3201/eid2511.180628 DO - 10.3201/eid2511.180628 ID - Kayem2019 ER - TY - STD TI - Gubareva LV, Kaiser L, Hayden FG. Influenza virus neuraminidase inhibitors. Lancet. 2000;355(9206):827–35. ID - ref28 ER - TY - JOUR AU - Xing, W. AU - Hejblum, G. AU - Leung, G. M. AU - Valleron, A. J. PY - 2010 DA - 2010// TI - Anatomy of the epidemiological literature on the 2003 SARS outbreaks in Hong Kong and Toronto: a time-stratified review JO - PLoS Med VL - 7 UR - https://doi.org/10.1371/journal.pmed.1000272 DO - 10.1371/journal.pmed.1000272 ID - Xing2010 ER - TY - JOUR AU - Ioannidis, J. P. AU - Manzoli, L. AU - Vito, C. AU - D'Addario, M. AU - Villari, P. PY - 2011 DA - 2011// TI - Publication delay of randomized trials on 2009 influenza A (H1N1) vaccination JO - PLoS One VL - 6 UR - https://doi.org/10.1371/journal.pone.0028346 DO - 10.1371/journal.pone.0028346 ID - Ioannidis2011 ER - TY - STD TI - World Health Organisation. WHO Statement on Public Disclosure of Clinical Trial Results 2015 [Available from: https://www.who.int/ictrp/results/WHO_Statement_results_reporting_clinical_trials.pdf?ua=1. Accessed 29 Apr 2020. UR - https://www.who.int/ictrp/results/WHO_Statement_results_reporting_clinical_trials.pdf?ua=1 ID - ref31 ER - TY - JOUR AU - Moorthy, V. S. AU - Karam, G. AU - Vannice, K. S. AU - Kieny, M. P. PY - 2015 DA - 2015// TI - Rationale for WHO’s new position calling for prompt reporting and public disclosure of interventional clinical trial results JO - PLoS Med VL - 12 UR - https://doi.org/10.1371/journal.pmed.1001819 DO - 10.1371/journal.pmed.1001819 ID - Moorthy2015 ER - TY - STD TI - The Lancet Editorial Team. 10+ 10: rapid decisions and fast track publication for RCTs. Lancet. 2015;385(9968):578. ID - ref33 ER - TY - JOUR AU - Button, K. S. AU - Bal, L. AU - Clark, A. AU - Shipley, T. PY - 2016 DA - 2016// TI - Preventing the ends from justifying the means: withholding results to address publication bias in peer-review JO - BMC Psychol VL - 4 UR - https://doi.org/10.1186/s40359-016-0167-7 DO - 10.1186/s40359-016-0167-7 ID - Button2016 ER - TY - JOUR AU - Kupferschmidt, K. PY - 2020 DA - 2020// TI - Preprints bring ‘firehose’ of outbreak data JO - Science. VL - 367 UR - https://doi.org/10.1126/science.367.6481.963 DO - 10.1126/science.367.6481.963 ID - Kupferschmidt2020 ER - TY - JOUR AU - Johansson, M. A. AU - Saderi, D. PY - 2020 DA - 2020// TI - Open peer-review platform for COVID-19 preprints JO - Nature. VL - 579 UR - https://doi.org/10.1038/d41586-020-00613-4 DO - 10.1038/d41586-020-00613-4 ID - Johansson2020 ER - TY - STD TI - The MIT Press and UC Berkeley launch rapid reviews: COVID-19 2020 [updated June 29 2020]. Available from: https://rapidreviewscovid19.mitpress.mit.edu/pub/press-release. UR - https://rapidreviewscovid19.mitpress.mit.edu/pub/press-release ID - ref37 ER - TY - JOUR AU - Zambon, M. PY - 2014 DA - 2014// TI - Developments in the treatment of severe influenza: lessons from the pandemic of 2009 and new prospects for therapy JO - Curr Opin Infect Dis VL - 27 UR - https://doi.org/10.1097/QCO.0000000000000113 DO - 10.1097/QCO.0000000000000113 ID - Zambon2014 ER - TY - JOUR AU - DeAngelis, C. D. AU - Drazen, J. M. AU - Frizelle, F. A. AU - Haug, C. AU - Hoey, J. AU - Horton, R. PY - 2004 DA - 2004// TI - Clinical trial registration: a statement from the International Committee of Medical Journal Editors JO - JAMA. VL - 292 UR - https://doi.org/10.1001/jama.292.11.1363 DO - 10.1001/jama.292.11.1363 ID - DeAngelis2004 ER -