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Table 2 Circulating IGF axis proteins levels

From: Insulin-like growth factor binding protein-2: a new circulating indicator of pulmonary arterial hypertension severity and survival

 

JHPH, N = 127

PAHB, N = 203

Control, N = 128

mean ± SD, p value

mean ± SD, p value

mean ± SD

(median; range)

(median; range)

(median; range)

IGF1 (ng/ml)

72.9 ± 30.4, p = 0.15

89.6 ± 51.3, p < 0.0001

69.4 ± 34.4

(67.0; 24.3–222.8)

(79.1; 21.6–486.6)

(64.7; 18.3–199.6)

IGF2 (ng/ml)

374.5 ± 121.9, p = 0.56

400.3 ± 182.8, p = 0.18

385.0 ± 171.6

(347.8; 56.1–908.1)

(391.6; 55.4–963.4)

(340.9; 56.6–994.5)

IGFBP2 (ng/ml)

419.8 ± 307.4, p < 0.0001

621.2 ± 425.9, p < 0.0001

207.3 ± 180.5

(350.9; 55.5–1869)

(474.6; 103.6–2144)

(170.2; 55.6–1806)

  1. p value was calculated by Mann-Whitney test between the values from PAH and control cohorts
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BMC Medicine

ISSN: 1741-7015

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