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Fig. 6 | BMC Medicine

Fig. 6

From: Immediate and durable effects of maternal tobacco consumption alter placental DNA methylation in enhancer and imprinted gene-containing regions

Fig. 6

Volcano plots showing the percent change in DNA methylation of each CpG included in the DMRs found near and/or overlapping with the 10 imprinted genes clusters (16 genes) as a function of the nominal p value (uncorrected p value of the EWAS). Three differential analyses are shown: smokers versus non-smokers (a), smokers versus former smokers (b) and former smokers versus non-smokers (c). Results were adjusted for child sex, parity, education level, season of conception, study center, maternal body mass index before pregnancy, maternal age at delivery, gestational duration, paternal smoking status at conception, batch, plate and chip, and estimated cellular heterogeneity

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BMC Medicine

ISSN: 1741-7015

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