Fig. 2

Location of study sites in a systematic review of published aetiological studies and case reports from Africa, 1980–2015. Legend: Location of study sites reported on in this review (in blue) augmented with major cities (in red). Data on major cities were obtained from “maps” package in R software, and for the purpose of this review, only cities with population greater than 100,000 are shown. Case series included individual case reports or series of patients with the same condition. Studies were classed as fever series if the total population denominator tested was reported. Seroprevalence studies were those where serum samples were tested for one pathogen or a panel of pathogens simultaneously