Skip to main content

Table 2 Mean frailty index, 99th centile, and proportion of participants in frailty categories for each trial: whole trial population and those over 65 years

From: Identifying frailty in trials: an analysis of individual participant data from trials of novel pharmacological interventions

Trial

Whole sample

Participants aged ≥ 65 years

Number missing (%)

Mean frailty index

99th centile

Frailty index categories (%)

Mean frailty index

99th centile

Frailty index categories (%)

0–0.12

0.12–0.24

0.24–0.36

> 0.36

0–0.12

0.12–0.24

0.24–0.36

> 0.36

Type 2 diabetes

 NCT01106625

0.16

0.35

31.36

56.12

11.82

0.7

0.17

0.51

24.38

63.68

8.81

3.13

74 (16%)

 NCT01106677

0.16

0.35

28.26

59.79

11.21

0.74

0.17

0.33

20.13

70.29

9.08

0.5

124 (10%)

 NCT00734474

0.13

0.35

54.22

39.24

5.72

0.82

0.14

0.32

43.78

49.08

6.81

0.33

66 (5%)

 NCT01064687

0.17

0.45

26.9

56.56

13.44

3.1

0.19

0.46

20.49

57.86

17.54

4.1

4 (0.4%)

 NCT01075282

0.16

0.42

33.35

53.02

11.29

2.34

0.18

0.42

23.2

57.15

16.72

2.93

4 (0.5%)

 NCT01191268

0.18

0.43

20.73

58.29

17.82

3.16

0.2

0.42

14.96

60.54

21.21

3.29

2 (0.2%)

 NCT01624259

0.16

0.45

35.34

51.53

10.36

2.77

0.18

0.43

24.7

55.16

16.94

3.2

1 (0.2%)

RA

 NCT00236028

0.26

0.41

2.62

37.05

53.73

6.6

0.27

0.41

1.15

28.08

61.5

9.27

12 (2%)

 NCT00264537

0.28

0.44

1.14

25.99

58.83

14.05

0.31

0.46

0.16

15.63

63.43

20.78

4 (0.6%)

 NCT00264550

0.27

0.45

2.03

34.71

51.37

11.89

0.28

0.41

3.58

24.91

57.11

14.41

2 (0.5%)

 NCT00361335

0.28

0.45

1.49

29.24

55.43

13.85

0.29

0.46

0.73

26.31

56.99

15.96

1 (0.2%)

 NCT00106535

0.22

0.4

11.57

46.97

37.19

4.27

0.24

0.4

9.73

39.92

44.71

5.64

4 (0.3%)

 NCT01007435

0.2

0.4

18.92

47.79

29.95

3.35

0.21

0.41

15.89

46.55

32.81

4.75

9 (3%)

 NCT01119859

0.24

0.44

8.5

43.27

39.88

8.36

0.25

0.48

7.07

40.41

40.3

12.22

3 (0.3%)

 NCT01232569

0.22

0.4

10.32

49.31

36.44

3.93

0.23

0.4

7.59

47.37

41.24

3.8

0 (0%)

COPD

 NCT01316900

0.18

0.35

24.62

55.68

18.9

0.8

0.17

0.35

25.83

57.28

16.3

0.58

33 (4%)

 NCT01316913

0.18

0.35

22.04

55.71

21.56

0.69

0.18

0.35

24.64

55.33

19.38

0.65

19 (2%)

 NCT01957163

0.17

0.37

27.13

55.71

15.74

1.42

0.17

0.36

28.32

56.89

13.79

1

0 (0%)

 NCT02119286

0.16

0.35

30.74

53.91

14.67

0.68

0.16

0.33

30.75

56.81

12.1

0.34

2 (0.3%)