Fig. 1

Genetic and environmental variance component estimates for anxiety and depression symptoms at age 8, from pedigree and RDR models. Coloured labels for the pedigree model refer to variance explained by genetic effects (i.e. pedigree heritability; yellow) and variance explained by shared environmental influences that increase resemblance among siblings in the same family (light green). Not shown: residual variance, which includes non-shared environmental effects and error. The effect of any covariance between genetic and shared environmental influences is not estimated in the pedigree model. Coloured labels for the RDR model refer to variance explained by direct child genetic effects (yellow), parent genetic effects (i.e. genetic nurture; dark green) and by covariance between the direct and nurturing genetic effects (‘Both’; grey). Not shown: residual variance affecting the phenotypes, including parent genetic effects not tagged by common SNPs, individual-specific environmental effects, chance factors and error. Sample sizes were ~ 27,000 pairs of related children for the pedigree model and ~ 11,600 genotyped parent-child trios for RDR. Bars = standard errors