Table 2 Summary of predictors of probability of censoring (Possible, Unlikely, or Highly Unlikely FoR events) within time interval from logistic regression weight determining model. Table shows odds ratios and 95% confidence intervals from multi-variable logistic regression model. Odds ratios adjusted also for country of site and cubic spline (3 knots) of time-varying baseline hazard
From: Investigation of the efficacy of the short regimen for rifampicin-resistant TB from the STREAM trial
Covariate | Level | Short regimen odds ratio (95% CI) | Long regimen odds ratio (95% CI) |
|---|---|---|---|
Time varying: cumulative number of grade 3–5 AEs | 0 | Reference | Reference |
1 | 4.1 (1.2, 13.5) | 6.2 (2.6, 15.2) | |
2 | 13.3 (3.2, 54.9) | 4.6 (1.4, 15.5) | |
3 | 16.4 (2.8, 95.7) | 11.5 (2.7, 50.0) | |
4 or more | 21.1 (3.3, 136.2) | 28.7 (4.0, 204.9) | |
Time varying: most recent culture was positive | 0.3 (0.0, 2.8) | 3.4 (1.3, 8.6) | |
HIV positive at baseline | 0.7 (0.2, 2.5) | 1.9 (0.7, 5.4) | |
Baseline smear grading | Negative, Scanty, 1+ | Reference | Reference |
2+ | 1.3 (0.4, 3.9) | 0.5 (0.2, 1.3) | |
3+ | 0.3 (0.1, 1.1) | 0.2 (0.1, 0.6) | |
BMI at baseline, per 1 kg/m2 | 0.91 (0.77, 1.08) | 0.87 (0.77, 0.99) | |
Age at baseline, per 1 year | 1.01 (0.97, 1.06) | 0.99 (0.96, 1.03) | |
Number of cavities on chest x-ray at baseline | None | Reference | Reference |
1 | 1.1 (0.2, 7.3) | 0.4 (0, 3.1) | |
2 or more | 1.7 (0.5, 5.9) | 1.2 (0.5, 3.2) | |