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Table 2 Summary of predictors of probability of censoring (Possible, Unlikely, or Highly Unlikely FoR events) within time interval from logistic regression weight determining model. Table shows odds ratios and 95% confidence intervals from multi-variable logistic regression model. Odds ratios adjusted also for country of site and cubic spline (3 knots) of time-varying baseline hazard

From: Investigation of the efficacy of the short regimen for rifampicin-resistant TB from the STREAM trial

Covariate Level Short regimen odds ratio (95% CI) Long regimen odds ratio (95% CI)
Time varying: cumulative number of grade 3–5 AEs 0 Reference Reference
1 4.1 (1.2, 13.5) 6.2 (2.6, 15.2)
2 13.3 (3.2, 54.9) 4.6 (1.4, 15.5)
3 16.4 (2.8, 95.7) 11.5 (2.7, 50.0)
4 or more 21.1 (3.3, 136.2) 28.7 (4.0, 204.9)
Time varying: most recent culture was positive 0.3 (0.0, 2.8) 3.4 (1.3, 8.6)
HIV positive at baseline 0.7 (0.2, 2.5) 1.9 (0.7, 5.4)
Baseline smear grading Negative, Scanty, 1+ Reference Reference
2+ 1.3 (0.4, 3.9) 0.5 (0.2, 1.3)
3+ 0.3 (0.1, 1.1) 0.2 (0.1, 0.6)
BMI at baseline, per 1 kg/m2 0.91 (0.77, 1.08) 0.87 (0.77, 0.99)
Age at baseline, per 1 year 1.01 (0.97, 1.06) 0.99 (0.96, 1.03)
Number of cavities on chest x-ray at baseline None Reference Reference
1 1.1 (0.2, 7.3) 0.4 (0, 3.1)
2 or more 1.7 (0.5, 5.9) 1.2 (0.5, 3.2)