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Table 2 Relevant baseline variables according to the serum B12 group

From: Relationship between serum B12 concentrations and mortality: experience in NHANES

  Serum B12 level (pmol/l) p value
  < 140 140–300 300–700 > 700
M/F 284/310 4442/4092 6827/6639 608/1060  
% females 52.2 47.9 49.3 63.5 9.0 × 10−25
Age 18–39 years (%) 23.1 38.2 39.2 21.1 1.0 × 10−71
Age 40–59 years (%) 30.3 31.3 30.0 31.3
Age ≥ 60 years (%) 46.6 30.5 30.8 47.6
Body mass index (kg/m2) 28.8 ± 6.8 29.1 ± 7.0 28.2 ± 6.5 27.9 ± 6.3 4.7 × 10−23
Waist circumference (cm) 100 ± 16 99 ± 16 96 ± 16 96 ± 15 1.2 × 10−37
SBP (mmHg) 128 ± 20 125 ± 19 124 ± 19 127 ± 21 1.0 × 10−12
DBP (mmHg) 70 ± 11 71 ± 12 70 ± 12 70 ± 12 1.1 × 10−4
C-reactive protein (mg/dl) 0.20 (0.09–0.44) 0.21 (0.08–0.50) 0.20 (0.08–0.47) 0.24 (0.09–0.56) 0.006
Serum folate (nmol/l) 34.1 (24.2–46.0) 34.3 (24.7–46.8) 41.9 (30.0–58.0) 55.1 (37.1–77.8) 3.0 × 10−209
Methylmalonic acid (nmol/l)1 272 (172–522) 150 (112–207) 124 (98–162) 122 (94–160) 3.8 × 10−194
Homocysteine (μmol/l)2 13.0 (9.5–18.3) 8.7 (7.1–11.0) 7.7 (6.4–9.4) 7.3 (5.8–9.1) 8.8 × 10−109
Annual family income      0.035
 < 25k (%) 43.8 39.6 37.9 38.1
 25–75k (%) 39.1 40.1 41.2 40.8
 > 75k (%) 17.1 20.3 20.9 21.1
Never smoking (%) 51.1 47.0 51.3 56.9 8.7 × 10−15
Former smoking (%) 21.5 20.9 21.3 25.4 0.001
Current smoking (%) 26.4 30.0 24.9 16.7 9.3 × 10−33
Use of vitamin B12-containing supplements (%) 17.0 20.3 35.2 59.5 2.6 × 10−264
Diabetes diagnosis (%) 21.9 15.2 15.3 22.8 8.6 × 10−18
Hypertension diagnosis (%) 43.1 34.3 32.6 45.4 4.3 × 10−28
Lipid diagnosis (%) 32.8 29.9 29.7 37.0 1.3 × 10−8
CVD diagnosis (%) 16.5 10.4 9.9 15.0 2.0 × 10−13
Cancer diagnosis (%) 10.1 7.6 7.9 11.5 4.8 × 10−7
Lung diagnosis (%) 14.5 11.7 11.3 13.9 0.002
  1. Data are presented as mean ± SD, median (IQR), numbers, or percentages
  2. 1In n = 19,492
  3. 2In n = 13,681