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Table 2 Proportions of preventable medication harm by medication class

From: Preventable medication harm across health care settings: a systematic review and meta-analysis

Drug class ATC code N studies Prevalence, % 95% CI τ2 I2 (%)
Analgesics N02¥ 4 7 0.5, 19 0.0229 84.00
Antibiotics and antibacterial J01¥ 12 12 7, 18 0.0165 87.80
Antithrombotic agents/anticoagulants B01¥ 10 11 7, 15 0.0073 78.60
Antidepressants N06Aβ 4 6 0.4, 17 0.0253 94.90
Antidiabetic A10¥ 4 7 0.8, 17 0.0162 77.50
Antiepileptics N03¥ 3 4 0.2, 10 0.0029 26.40
Anti-inflammatory and antirheumatic M01¥ 5 15 7, 26 0.0166 79.40
Antipsychotics N05Aβ 4 11 0.2, 32 0.0622 95.60
Cardiovascular C* 14 16 11, 23 0.0205 90.80
Corticosteroids H02¥ 5 2 0.2, 6 0.0066 77.10
Diuretics C03¥ 5 6 0.2, 17 0.0365 95.80
Functional gastrointestinal disorders A03¥ 3 4 0, 14 0.0183 75.80
Musculoskeletal system M* 3 9 2.4, 20 0.0142 85.00
Nervous system N* 6 21 6, 43 0.0784 97.00
Opioids N02Aβ 5 6 2, 10 0.0045 74.70
Respiratory system-related drugs R* 4 1 0, 4 0.0061 74.90
Sedatives N05Cβ 5 16 11, 21 0.0016 33.50
  1. *ATC 1st level—related to mostly body function;
  2. ¥ATC 2nd level—pharmacological or therapeutic subgroup
  3. βATC 3rd and 4th levels—chemical, pharmacological or therapeutic subgroup