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Fig. 1 | BMC Medicine

Fig. 1

From: Modelling the household-level impact of a maternal respiratory syncytial virus (RSV) vaccine in a high-income setting

Fig. 1

Schematic diagram of the epidemiological model. An infant is assigned one of three states at birth: a maternally protected state from the mother having been vaccinated (MV), a maternally protected state from the mother having experienced a recent infection (MI), or a fully susceptible state (S). If an infant would otherwise have both types of maternal protection, they are born into the MV class. If exposed to infection (where exposure is scaled according to whether the infant has maternal protection), the infant moves to the exposed class (E), from which they progress to being infectious (I), and then to recovered (R). Vaccination of pregnant women can occur at any of the susceptible, exposed, infectious, or recovered states. Vaccinated individuals become fully protected from infection (R). Fully protected individuals lose protection over time and become fully susceptible once protection is completely lost. Parameter values are reported in Table 1

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