Fig. 4

Serum CYFRA21-1 levels as an indicator of 90-day transplant-free survival in hospitalized patients with decompensated cirrhosis and ascites (cohort iv). Two hundred eighty patients who were hospitalized for decompensated cirrhosis and ascites were analyzed. Kaplan-Meier curves depict the cumulative 90-day transplant-free survival for serum CYFRA21-1 levels dichotomized at 12.19 ng/mL (a) and for quartiles of serum CYFRA21-1 concentrations (≤ 0.2 ng/mL, 0.2–5.4 ng/mL, 5.4–11.0 ng/mL, > 11.0 ng/mL) (b). Unadjusted hazard ratios (HRs) with their 95% confidence intervals [in brackets] and log-rank P values are shown in the corresponding graphs. c Sensitivity analysis of serum CYFRA21-1 for predicting 90-day transplant-free survival in indicated subgroups. Unadjusted hazard ratios (HRs) and 95% confidence intervals are displayed. Abbreviations: ACLF, acute-on-chronic liver failure; ALD, alcoholic liver disease; SBP, spontaneous bacterial peritonitis; HCC, hepatocellular carcinoma; MELD, model of end-stage liver disease