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Table 1 Posterior distributions of the model parameters used in the transmission model of RSV. CrI credible interval

From: Evaluating the next generation of RSV intervention strategies: a mathematical modelling study and cost-effectiveness analysis

 

Parameter

Mean value (95% CrI of posterior where applicable)

Reference for fixed value or prior distribution

μ

Daily number of live births

1863 (fixed)

[8]

1/ξ

Average duration of maternally derived immunity (days)

133.5 (119.6–146.1)

[19,20,21]

1/ω

Average duration of post-infection immunity (days)

358.9 (350.7–364.7)

[22, 23]

1/σ

Average duration of exposure (days)

4.98 (4.54–5.37)

[24]

1/γ0

Average duration of primary infection (days)

6.16 (5.68–6.63)

[15]

g1

Decrease in secondary infection duration relative to primary

0.87 (0.83–0.91)

[15]

g2

Decrease in subsequent infection duration relative to secondary

0.79 (0.73–0.86)

[15, 24]

p<1

Proportion asymptomatic (< 1 years)

0.0916 (0.031–0.158)

[13]

p1–4

Proportion asymptomatic (1–4 years)

0.163 (0.092–0.223)

[13]

p5–14

Proportion asymptomatic (5–14 years)

0.516 (0.460–0.572)

[13]

p15+

Proportion asymptomatic (15+ years)

0.753 (0.656–0.829)

[13]

α

Relative reduction in infectiousness for asymptomatic infections

0.634 (0.541–0.724)

Fitted

qp

Probability of RSV transmission per physical contact

0.0972 (0.093–0.099)

Fitted

qc

Relative reduction in probability of RSV transmission per conversational contact compared to physical contact

0.998 (0.996–1.000)

Fitted

b1

Relative amplitude of transmission during peak

1.998 (1.992–2.000)

Fitted

φ

Seasonal shift in transmission

0.614 (0.607–0.624)

Fitted

ψ

Seasonality wavelength constant

0.236 (0.220–0.252)

Fitted

Susceptibility

 δ1

Secondary infection (relative to primary)

0.89 (0.85–0.93)

[14]

 δ2

Tertiary infection (relative to secondary)

0.81 (0.74–0.85)

[14]

 δ3

Subsequent infections (relative to tertiary)

0.33 (0.31–0.37)

[14]

Probability that an RSV infection is reported

 ϵj

0–4 years

exp(− 4.602–0.233j)

[14, 25]

 ϵ17

5–54 years

0.0000305 (0.0000290–0.0000320)

[22]

 ϵ18

55+ years

0.000147 (0.000134–0.000160)

[22]