TY - JOUR AU - Mehlen, P. AU - Puisieux, A. PY - 2006 DA - 2006// TI - Metastasis: a question of life or death JO - Nat Rev Cancer VL - 6 UR - https://doi.org/10.1038/nrc1886 DO - 10.1038/nrc1886 ID - Mehlen2006 ER - TY - JOUR AU - McBryan, J. AU - Fagan, A. AU - McCartan, D. AU - Bane, F. T. AU - Vareslija, D. AU - Cocchiglia, S. PY - 2015 DA - 2015// TI - Transcriptomic profiling of sequential tumors from breast cancer patients provides a global view of metastatic expression changes following endocrine therapy JO - Clin Cancer Res VL - 21 UR - https://doi.org/10.1158/1078-0432.CCR-14-2155 DO - 10.1158/1078-0432.CCR-14-2155 ID - McBryan2015 ER - TY - JOUR AU - Vareslija, D. AU - Priedigkeit, N. AU - Fagan, A. AU - Purcell, S. AU - Cosgrove, N. AU - O'Halloran, P. J. PY - 2019 DA - 2019// TI - Transcriptome characterization of matched primary breast and brain metastatic tumors to detect novel actionable targets JO - J Natl Cancer Inst VL - 111 UR - https://doi.org/10.1093/jnci/djy110 DO - 10.1093/jnci/djy110 ID - Vareslija2019 ER - TY - JOUR AU - Mead, T. J. AU - Apte, S. S. PY - 2018 DA - 2018// TI - ADAMTS proteins in human disorders JO - Matrix Biol VL - 71–72 UR - https://doi.org/10.1016/j.matbio.2018.06.002 DO - 10.1016/j.matbio.2018.06.002 ID - Mead2018 ER - TY - JOUR AU - Turner, S. L. AU - Blair-Zajdel, M. E. AU - Bunning, R. A. PY - 2009 DA - 2009// TI - ADAMs and ADAMTSs in cancer JO - Br J Biomed Sci VL - 66 UR - https://doi.org/10.1080/09674845.2009.11730257 DO - 10.1080/09674845.2009.11730257 ID - Turner2009 ER - TY - JOUR AU - Edwards, D. R. AU - Handsley, M. M. AU - Pennington, C. J. PY - 2008 DA - 2008// TI - The ADAM metalloproteinases JO - Mol Asp Med VL - 29 UR - https://doi.org/10.1016/j.mam.2008.08.001 DO - 10.1016/j.mam.2008.08.001 ID - Edwards2008 ER - TY - JOUR AU - Reiss, K. AU - Saftig, P. PY - 2009 DA - 2009// TI - The “a disintegrin and metalloprotease” (ADAM) family of sheddases: physiological and cellular functions JO - Semin Cell Dev Biol VL - 20 UR - https://doi.org/10.1016/j.semcdb.2008.11.002 DO - 10.1016/j.semcdb.2008.11.002 ID - Reiss2009 ER - TY - JOUR AU - Murphy, G. PY - 2008 DA - 2008// TI - The ADAMs: signalling scissors in the tumour microenvironment JO - Nat Rev Cancer VL - 8 UR - https://doi.org/10.1038/nrc2459 DO - 10.1038/nrc2459 ID - Murphy2008 ER - TY - JOUR AU - Duffy, M. J. AU - Mullooly, M. AU - O'Donovan, N. AU - Sukor, S. AU - Crown, J. AU - Pierce, A. PY - 2011 DA - 2011// TI - The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer? JO - Clin Proteomics VL - 8 UR - https://doi.org/10.1186/1559-0275-8-9 DO - 10.1186/1559-0275-8-9 ID - Duffy2011 ER - TY - JOUR AU - McCartan, D. AU - Bolger, J. C. AU - Fagan, A. AU - Byrne, C. AU - Hao, Y. AU - Qin, L. PY - 2012 DA - 2012// TI - Global characterization of the SRC-1 transcriptome identifies ADAM22 as an ER-independent mediator of endocrine-resistant breast cancer JO - Cancer Res VL - 72 UR - https://doi.org/10.1158/0008-5472.CAN-11-1976 DO - 10.1158/0008-5472.CAN-11-1976 ID - McCartan2012 ER - TY - JOUR AU - Li, J. AU - Lu, M. AU - Jin, J. AU - Lu, X. AU - Xu, T. AU - Jin, S. PY - 2018 DA - 2018// TI - miR-449a suppresses tamoxifen resistance in human breast cancer cells by targeting ADAM22 JO - Cell Physiol Biochem VL - 50 UR - https://doi.org/10.1159/000493964 DO - 10.1159/000493964 ID - Li2018 ER - TY - JOUR AU - Liu, H. AU - Shim, A. H. AU - He, X. PY - 2009 DA - 2009// TI - Structural characterization of the ectodomain of a disintegrin and metalloproteinase-22 (ADAM22), a neural adhesion receptor instead of metalloproteinase: insights on ADAM function JO - J Biol Chem VL - 284 UR - https://doi.org/10.1074/jbc.M109.014258 DO - 10.1074/jbc.M109.014258 ID - Liu2009 ER - TY - JOUR AU - Fukata, Y. AU - Lovero, K. L. AU - Iwanaga, T. AU - Watanabe, A. AU - Yokoi, N. AU - Tabuchi, K. PY - 2010 DA - 2010// TI - Disruption of LGI1-linked synaptic complex causes abnormal synaptic transmission and epilepsy JO - Proc Natl Acad Sci U S A VL - 107 UR - https://doi.org/10.1073/pnas.0914537107 DO - 10.1073/pnas.0914537107 ID - Fukata2010 ER - TY - JOUR AU - Bolger, J. C. AU - Young, L. S. PY - 2013 DA - 2013// TI - ADAM22 as a prognostic and therapeutic drug target in the treatment of endocrine-resistant breast cancer JO - Vitam Horm VL - 93 UR - https://doi.org/10.1016/B978-0-12-416673-8.00014-9 DO - 10.1016/B978-0-12-416673-8.00014-9 ID - Bolger2013 ER - TY - JOUR AU - Chernova, O. B. AU - Somerville, R. P. AU - Cowell, J. K. PY - 1998 DA - 1998// TI - A novel gene, LGI1, from 10q24 is rearranged and downregulated in malignant brain tumors JO - Oncogene. VL - 17 UR - https://doi.org/10.1038/sj.onc.1202481 DO - 10.1038/sj.onc.1202481 ID - Chernova1998 ER - TY - JOUR AU - Kodack, D. P. AU - Askoxylakis, V. AU - Ferraro, G. B. AU - Fukumura, D. AU - Jain, R. K. PY - 2015 DA - 2015// TI - Emerging strategies for treating brain metastases from breast cancer JO - Cancer Cell VL - 27 UR - https://doi.org/10.1016/j.ccell.2015.01.001 DO - 10.1016/j.ccell.2015.01.001 ID - Kodack2015 ER - TY - JOUR AU - Bronzert, D. A. AU - Greene, G. L. AU - Lippman, M. E. PY - 1985 DA - 1985// TI - Selection and characterization of a breast cancer cell line resistant to the antiestrogen LY 117018 JO - Endocrinology. VL - 117 UR - https://doi.org/10.1210/endo-117-4-1409 DO - 10.1210/endo-117-4-1409 ID - Bronzert1985 ER - TY - JOUR AU - Ward, E. AU - Vareslija, D. AU - Charmsaz, S. AU - Fagan, A. AU - Browne, A. L. AU - Cosgrove, N. PY - 2018 DA - 2018// TI - Epigenome-wide SRC-1-mediated gene silencing represses cellular differentiation in advanced breast cancer JO - Clin Cancer Res VL - 24 UR - https://doi.org/10.1158/1078-0432.CCR-17-2615 DO - 10.1158/1078-0432.CCR-17-2615 ID - Ward2018 ER - TY - JOUR AU - Vareslija, D. AU - McBryan, J. AU - Fagan, A. AU - Redmond, A. M. AU - Hao, Y. AU - Sims, A. H. PY - 2016 DA - 2016// TI - Adaptation to AI therapy in breast cancer can induce dynamic alterations in ER activity resulting in estrogen-independent metastatic tumors JO - Clin Cancer Res VL - 22 UR - https://doi.org/10.1158/1078-0432.CCR-15-1583 DO - 10.1158/1078-0432.CCR-15-1583 ID - Vareslija2016 ER - TY - STD TI - Priedigkeit N, Watters RJ, Lucas PC, Basudan A, Bhargava R, Horne W, et al. Exome-capture RNA sequencing of decade-old breast cancers and matched decalcified bone metastases. JCI insight. 2017;2(17). ID - ref20 ER - TY - JOUR AU - Patro, R. AU - Duggal, G. AU - Love, M. I. AU - Irizarry, R. A. AU - Kingsford, C. PY - 2017 DA - 2017// TI - Salmon provides fast and bias-aware quantification of transcript expression JO - Nat Methods VL - 14 UR - https://doi.org/10.1038/nmeth.4197 DO - 10.1038/nmeth.4197 ID - Patro2017 ER - TY - JOUR AU - Love, M. I. AU - Huber, W. AU - Anders, S. PY - 2014 DA - 2014// TI - Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 JO - Genome Biol VL - 15 UR - https://doi.org/10.1186/s13059-014-0550-8 DO - 10.1186/s13059-014-0550-8 ID - Love2014 ER - TY - JOUR AU - Naba, A. AU - Clauser, K. R. AU - Ding, H. AU - Whittaker, C. A. AU - Carr, S. A. AU - Hynes, R. O. PY - 2016 DA - 2016// TI - The extracellular matrix: tools and insights for the “omics” era JO - Matrix Biol VL - 49 UR - https://doi.org/10.1016/j.matbio.2015.06.003 DO - 10.1016/j.matbio.2015.06.003 ID - Naba2016 ER - TY - JOUR AU - Robinson, M. D. AU - McCarthy, D. J. AU - Smyth, G. K. PY - 2010 DA - 2010// TI - edgeR: a Bioconductor package for differential expression analysis of digital gene expression data JO - Bioinformatics. VL - 26 UR - https://doi.org/10.1093/bioinformatics/btp616 DO - 10.1093/bioinformatics/btp616 ID - Robinson2010 ER - TY - JOUR AU - Yu, G. AU - Wang, L. G. AU - Han, Y. AU - He, Q. Y. PY - 2012 DA - 2012// TI - clusterProfiler: an R package for comparing biological themes among gene clusters JO - OMICS. VL - 16 UR - https://doi.org/10.1089/omi.2011.0118 DO - 10.1089/omi.2011.0118 ID - Yu2012 ER - TY - JOUR AU - Cotto, K. C. AU - Wagner, A. H. AU - Feng, Y. Y. AU - Kiwala, S. AU - Coffman, A. C. AU - Spies, G. PY - 2018 DA - 2018// TI - DGIdb 3.0: a redesign and expansion of the drug-gene interaction database JO - Nucleic Acids Res VL - 46 UR - https://doi.org/10.1093/nar/gkx1143 DO - 10.1093/nar/gkx1143 ID - Cotto2018 ER - TY - JOUR AU - Gu, Z. AU - Eils, R. AU - Schlesner, M. PY - 2016 DA - 2016// TI - Complex heatmaps reveal patterns and correlations in multidimensional genomic data JO - Bioinformatics. VL - 32 UR - https://doi.org/10.1093/bioinformatics/btw313 DO - 10.1093/bioinformatics/btw313 ID - Gu2016 ER - TY - JOUR AU - Bos, P. D. AU - Zhang, X. H. AU - Nadal, C. AU - Shu, W. AU - Gomis, R. R. AU - Nguyen, D. X. PY - 2009 DA - 2009// TI - Genes that mediate breast cancer metastasis to the brain JO - Nature. VL - 459 UR - https://doi.org/10.1038/nature08021 DO - 10.1038/nature08021 ID - Bos2009 ER - TY - JOUR AU - Kanojia, D. AU - Morshed, R. A. AU - Zhang, L. AU - Miska, J. M. AU - Qiao, J. AU - Kim, J. W. PY - 2015 DA - 2015// TI - βIII-Tubulin regulates breast cancer metastases to the brain JO - Mol Cancer Ther VL - 14 UR - https://doi.org/10.1158/1535-7163.MCT-14-0950 DO - 10.1158/1535-7163.MCT-14-0950 ID - Kanojia2015 ER - TY - JOUR AU - Shaw, F. L. AU - Harrison, H. AU - Spence, K. AU - Ablett, M. P. AU - Simoes, B. M. AU - Farnie, G. PY - 2012 DA - 2012// TI - A detailed mammosphere assay protocol for the quantification of breast stem cell activity JO - J Mammary Gland Biol Neoplasia VL - 17 UR - https://doi.org/10.1007/s10911-012-9255-3 DO - 10.1007/s10911-012-9255-3 ID - Shaw2012 ER - TY - JOUR AU - Browne, A. L. AU - Charmsaz, S. AU - Vareslija, D. AU - Fagan, A. AU - Cosgrove, N. AU - Cocchiglia, S. PY - 2018 DA - 2018// TI - Network analysis of SRC-1 reveals a novel transcription factor hub which regulates endocrine resistant breast cancer JO - Oncogene. VL - 37 UR - https://doi.org/10.1038/s41388-017-0042-x DO - 10.1038/s41388-017-0042-x ID - Browne2018 ER - TY - JOUR AU - McBryan, J. AU - Theissen, S. M. AU - Byrne, C. AU - Hughes, E. AU - Cocchiglia, S. AU - Sande, S. PY - 2012 DA - 2012// TI - Metastatic progression with resistance to aromatase inhibitors is driven by the steroid receptor coactivator SRC-1 JO - Cancer Res VL - 72 UR - https://doi.org/10.1158/0008-5472.CAN-11-2073 DO - 10.1158/0008-5472.CAN-11-2073 ID - McBryan2012 ER - TY - JOUR AU - Charmsaz, S. AU - Hughes, E. AU - Bane, F. T. AU - Tibbitts, P. AU - McIlroy, M. AU - Byrne, C. PY - 2017 DA - 2017// TI - S100beta as a serum marker in endocrine resistant breast cancer JO - BMC Med VL - 15 UR - https://doi.org/10.1186/s12916-017-0836-2 DO - 10.1186/s12916-017-0836-2 ID - Charmsaz2017 ER - TY - JOUR AU - Sachs, N. AU - Ligt, J. AU - Kopper, O. AU - Gogola, E. AU - Bounova, G. AU - Weeber, F. PY - 2018 DA - 2018// TI - A living biobank of breast cancer organoids captures disease heterogeneity JO - Cell VL - 172 UR - https://doi.org/10.1016/j.cell.2017.11.010 DO - 10.1016/j.cell.2017.11.010 ID - Sachs2018 ER - TY - JOUR AU - Marino, A. AU - Almici, E. AU - Migliorin, S. AU - Tapeinos, C. AU - Battaglini, M. AU - Cappello, V. PY - 2019 DA - 2019// TI - Piezoelectric barium titanate nanostimulators for the treatment of glioblastoma multiforme JO - J Colloid Interface Sci VL - 538 UR - https://doi.org/10.1016/j.jcis.2018.12.014 DO - 10.1016/j.jcis.2018.12.014 ID - Marino2019 ER - TY - JOUR AU - Fukata, Y. AU - Adesnik, H. AU - Iwanaga, T. AU - Bredt, D. S. AU - Nicoll, R. A. AU - Fukata, M. PY - 2006 DA - 2006// TI - Epilepsy-related ligand/receptor complex LGI1 and ADAM22 regulate synaptic transmission JO - Science. VL - 313 UR - https://doi.org/10.1126/science.1129947 DO - 10.1126/science.1129947 ID - Fukata2006 ER - TY - JOUR AU - Kimbung, S. AU - Johansson, I. AU - Danielsson, A. AU - Veerla, S. AU - Egyhazi Brage, S. AU - Frostvik Stolt, M. PY - 2016 DA - 2016// TI - Transcriptional profiling of breast cancer metastases identifies liver metastasis-selective genes associated with adverse outcome in luminal a primary breast cancer JO - Clin Cancer Res VL - 22 UR - https://doi.org/10.1158/1078-0432.CCR-15-0487 DO - 10.1158/1078-0432.CCR-15-0487 ID - Kimbung2016 ER - TY - JOUR AU - Conrad, C. AU - Benzel, J. AU - Dorzweiler, K. AU - Cook, L. AU - Schlomann, U. AU - Zarbock, A. PY - 2019 DA - 2019// TI - ADAM8 in invasive cancers: links to tumor progression, metastasis, and chemoresistance JO - Clin Sci (Lond) VL - 133 UR - https://doi.org/10.1042/CS20180906 DO - 10.1042/CS20180906 ID - Conrad2019 ER - TY - JOUR AU - Jones, D. H. AU - Ley, S. AU - Aitken, A. PY - 1995 DA - 1995// TI - Isoforms of 14-3-3 protein can form homo- and heterodimers in vivo and in vitro: implications for function as adapter proteins JO - FEBS Lett VL - 368 UR - https://doi.org/10.1016/0014-5793(95)00598-4 DO - 10.1016/0014-5793(95)00598-4 ID - Jones1995 ER - TY - JOUR AU - Zhu, P. AU - Sang, Y. AU - Xu, H. AU - Zhao, J. AU - Xu, R. AU - Sun, Y. PY - 2005 DA - 2005// TI - ADAM22 plays an important role in cell adhesion and spreading with the assistance of 14-3-3 JO - Biochem Biophys Res Commun VL - 331 UR - https://doi.org/10.1016/j.bbrc.2005.03.229 DO - 10.1016/j.bbrc.2005.03.229 ID - Zhu2005 ER - TY - JOUR AU - Zhu, P. AU - Sang, Y. AU - Xu, R. AU - Zhao, J. AU - Li, C. AU - Zhao, S. PY - 2002 DA - 2002// TI - The interaction between ADAM22 and 14-3-3beta JO - Sci China C Life Sci VL - 45 ID - Zhu2002 ER - TY - JOUR AU - Sternlicht, M. D. AU - Sunnarborg, S. W. PY - 2008 DA - 2008// TI - The ADAM17-amphiregulin-EGFR axis in mammary development and cancer JO - J Mammary Gland Biol Neoplasia VL - 13 UR - https://doi.org/10.1007/s10911-008-9084-6 DO - 10.1007/s10911-008-9084-6 ID - Sternlicht2008 ER - TY - JOUR AU - Gabellini, N. AU - Masola, V. AU - Quartesan, S. AU - Oselladore, B. AU - Nobile, C. AU - Michelucci, R. PY - 2006 DA - 2006// TI - Increased expression of LGI1 gene triggers growth inhibition and apoptosis of neuroblastoma cells JO - J Cell Physiol VL - 207 UR - https://doi.org/10.1002/jcp.20627 DO - 10.1002/jcp.20627 ID - Gabellini2006 ER - TY - JOUR AU - Bornstein, G. G. PY - 2015 DA - 2015// TI - Antibody drug conjugates: preclinical considerations JO - AAPS J VL - 17 UR - https://doi.org/10.1208/s12248-015-9738-4 DO - 10.1208/s12248-015-9738-4 ID - Bornstein2015 ER - TY - JOUR AU - Gabellini, N. AU - Masola, V. PY - 2009 DA - 2009// TI - Expression of LGI1 impairs proliferation and survival of HeLa cells JO - Int J Cell Biol VL - 2009 UR - https://doi.org/10.1155/2009/417197 DO - 10.1155/2009/417197 ID - Gabellini2009 ER - TY - JOUR AU - Kunapuli, P. AU - Kasyapa, C. S. AU - Hawthorn, L. AU - Cowell, J. K. PY - 2004 DA - 2004// TI - LGI1, a putative tumor metastasis suppressor gene, controls in vitro invasiveness and expression of matrix metalloproteinases in glioma cells through the ERK1/2 pathway JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M314192200 DO - 10.1074/jbc.M314192200 ID - Kunapuli2004 ER - TY - JOUR AU - Fosgerau, K. AU - Hoffmann, T. PY - 2015 DA - 2015// TI - Peptide therapeutics: current status and future directions JO - Drug Discov Today VL - 20 UR - https://doi.org/10.1016/j.drudis.2014.10.003 DO - 10.1016/j.drudis.2014.10.003 ID - Fosgerau2015 ER - TY - JOUR AU - Hyvonen, M. AU - Enback, J. AU - Huhtala, T. AU - Lammi, J. AU - Sihto, H. AU - Weisell, J. PY - 2014 DA - 2014// TI - Novel target for peptide-based imaging and treatment of brain tumors JO - Mol Cancer Ther VL - 13 UR - https://doi.org/10.1158/1535-7163.MCT-13-0684 DO - 10.1158/1535-7163.MCT-13-0684 ID - Hyvonen2014 ER - TY - JOUR AU - Marqus, S. AU - Pirogova, E. AU - Piva, T. J. PY - 2017 DA - 2017// TI - Evaluation of the use of therapeutic peptides for cancer treatment JO - J Biomed Sci VL - 24 UR - https://doi.org/10.1186/s12929-017-0328-x DO - 10.1186/s12929-017-0328-x ID - Marqus2017 ER - TY - JOUR AU - Liu, M. C. AU - Cortes, J. AU - O'Shaughnessy, J. PY - 2016 DA - 2016// TI - Challenges in the treatment of hormone receptor-positive, HER2-negative metastatic breast cancer with brain metastases JO - Cancer Metastasis Rev VL - 35 UR - https://doi.org/10.1007/s10555-016-9619-z DO - 10.1007/s10555-016-9619-z ID - Liu2016 ER - TY - JOUR AU - Hu, Y. AU - Yu, X. AU - Xu, G. AU - Liu, S. PY - 2017 DA - 2017// TI - Metastasis: an early event in cancer progression JO - J Cancer Res Clin Oncol VL - 143 UR - https://doi.org/10.1007/s00432-016-2279-0 DO - 10.1007/s00432-016-2279-0 ID - Hu2017 ER -