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Table 1 Clinical details of patients

From: Sleep in disorders of consciousness: behavioral and polysomnographic recording

ID

Age range (years)

Time since injury (days)

Medication (Sed, Stim, Anticon)

Etiology

EEG grade

CRS-r (A, V, M, OV, C, Ar)

UWS1

51–55

62

0, 0, 1

hypox

1

5 (1, 0, 2, 1, 0, 1)

UWS2

46–50

151

1, 0, 0

TBI

2

5 (1, 0, 1, 1, 0, 2)

UWS3

61–65

273

0, 0, 0

stroke

5

7 (2, 1, 2, 1, 0, 1)

UWS4

26–30

68

0, 0, 1

TBI

3

7 (2, 1, 1, 1, 0, 2)

UWS5

51–55

134

1, 0, 1

hypox

1

5 (1, 0, 1, 1, 0, 2)

UWS6

36–40

69

0, 1, 1

stroke

1

4 (1, 0, 0, 1, 0, 2)

UWS7

46–50

174

2, 0, 1

TBI

2

8 (2, 1, 2, 1, 0, 2)

UWS8

26–30

233

1, 0, 1

TBI

2

4 (1, 0, 1, 1, 0, 1)

UWS9

56–60

46

0, 0, 0

hypox

3

7 (2, 1, 2, 1, 0, 1)

UWS10

61–65

197

1, 1, 1

SAH

4

6 (1, 0, 2, 1, 0, 2)

UWS11

18–25

134

0, 0, 1

TBI

3

2 (0, 0, 0, 1, 0, 1)

UWS12

41–45

52

0, 0, 2

hypox

3

5 (1, 0, 1, 2, 0, 1)

UWS13

56–60

98

3, 0, 1

hypox

1

6 (2, 0, 2, 1, 0, 1)

UWS14

56–60

116

1, 1, 0

stroke

3

3 (0, 0, 2, 1, 0, 0)

UWS15

18–25

169

0, 1, 0

TBI

3

6 (2, 0, 1, 1, 0, 2)

UWS16

56–60

61

0, 0, 1

stroke

3

7 (2, 0, 2, 1, 0, 2)

MCS1

66–70

69

1, 0, 1

stroke

4

10 (2, 2, 2, 1, 1, 2)

MCS2

56–60

155

0, 0, 1

hypox

2

12 (2, 1, 5, 2, 1, 1)

MCS3

51–55

84

1, 1, 1

hypox

1

9 (2, 0, 2, 2, 1, 2)

MCS4

46–50

109

0, 2, 1

TBI

4

10 (2, 3, 2, 1, 0, 2)

MCS5

51–55

60

2, 0, 0

TBI

5

14 (3, 3, 5, 1, 1, 1)

MCS6

51–55

158

1, 1, 1

SAH

4

12 (2, 3, 2, 2, 1, 2)

MCS7

61–65

66

0, 1, 1

hypox

1

6 (2, 2, 0, 1, 0, 1)

MCS8

61–65

133

0, 1, 0

SAH

3

9 (2, 3, 2, 1, 0, 1)

MCS9

21–25

150

0, 1, 0

hypox

4

9 (1, 0, 5, 1, 0, 2)

MCS10

66–70

140

0, 1, 0

TBI

4

16 (2, 3, 5, 3, 1, 2)

MCS11

21–25

234

3, 0, 0

enceph

2

8 (0, 1, 4, 1, 0, 2)

MCS12

51–55

92

0, 0, 0

SAH

5

11 (2, 3, 2, 2, 0, 2)

MCS13

18–25

131

1, 0, 0

stroke

3

8 (1, 0, 5, 1, 0, 1)

MCS14

41–45

78

0, 1, 1

SAH

4

8 (1, 2, 2, 1, 0, 2)

MCS15

41–45

96

1, 1, 1

hypox

1

9 (2, 2, 2, 1, 0, 2)

MCS16

56–60

74

1, 0, 1

stroke

5

14 (3, 1, 5, 2, 1, 2)

CC1

51–55

155

1, 0, 0

–

–

–

CC2

26–30

1176

1, 0, 2

–

–

–

CC3

36–40

3876

1, 0, 1

–

–

–

CC4

18–25

379

1, 0, 1

–

–

–

CC5

65–70

33

0, 0, 0

–

–

–

CC6

61–65

267

1, 0, 1

–

–

–

CC7

51–55

131

1, 0, 0

–

–

–

CC8

66–70

96

1, 0, 1

–

–

–

CC9

26–30

682

0, 0, 0

–

–

–

CC10

18–25

163

1, 0, 0

–

–

–

  1. CRS-r total score of Coma Recovery Scale – revised, A auditory, V visual, M motor, OV oromotor/verbal, C communication, Ar arousal subscores. Etiology: TBI traumatic brain injury, hypox hypoxic brain injury, enceph encephalitis, SAH subarachnoid hemorrhage. Medication: the number of potentially sleep-affecting medicaments, Sed with muscle relaxation or sedative effects, Stim with stimulating effects, Anticon with anticonvulsive effects (see Additional file 1: Table S1 for a complete list of the medicaments). EEG grade: 1—low amplitude, basic rhythm is difficult to assess; 2—mixture of delta and low theta; 3—stable basic activity in the low-frequency theta domain (4–6 Hz); 4—high-frequency theta mixed with episodes of other rhythms but no desynchronization to visual and verbal stimulation; 5—stable basic activity at 7–8 Hz OR theta activity responsive to stimulation. Seven of the sixteen MCS patients (patients 4, 5, 6, 8, 10, 12, and 16) were MCS+, the other nine were MCS−