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Table 2 Characteristics of the population according to their COVID-19 test and the frailty phenotype

From: Comparison of two different frailty measurements and risk of hospitalisation or death from COVID-19: findings from UK Biobank

 

No COVID-19 associated admission or death

Severe COVID-19 infection

Robust

Pre-frail

Frail

Robust

Pre-frail

Frail

Total, n

228,731

142,550

11,762

354

374

74

Baseline age (years), mean (SD)

56.0 (8.1)

56.5 (8.1)

57.4 (7.7)

60.3 (7.7)

59.8 (7.8)

59.5 (7.9)

Current age (years), mean (SD)

67.1 (8.1)

67.5 (8.1)

68.4 (7.7)

71.3 (7.8)

70.8 (7.8)

70.6 (8.0)

Sex (female), n (%)

120,231 (52.6)

83,011 (58.2)

7772 (66.1)

116 (32.8)

145 (38.8)

35 (47.3)

Deprivation, n (%)

 Lower

83,333 (36.5)

42,368 (29.7)

2086 (17.7)

92 (26.0)

87 (23.3)

9 (12.1)

 Middle

78,557 (34.3)

46,199 (32.4)

2947 (25.1)

123 (34.7)

95 (25.4)

15 (20.3)

 Higher

66,841 (29.2)

53,983 (37.9)

6729 (57.2)

139 (39.3)

192 (51.3)

50 (67.6)

Ethnicity, n (%)

 White

220,508 (96.4)

132,223 (92.8)

10,204 (86.8)

325 (91.8)

324 (86.6)

63 (85.1)

 Non-white

8223 (3.6)

10,327 (7.2)

1558 (13.2)

29 (8.2)

50 (13.4)

11 (14.9)

Smoking status, n (%)

 Never

130,457 (57.0)

76,966 (54.0)

5737 (48.8)

134 (37.9)

177 (47.3)

25 (33.8)

 Previous

79,074 (34.6)

49,909 (35.0)

4021 (34.2)

173 (48.9)

151 (40.4)

37 (50.0)

 Current

19,200 (8.4)

15,675 (11.0)

2004 (17.0)

47 (13.2)

46 (12.3)

12 (16.2)

Alcohol intake, n (%)

 Daily or almost daily

53,467 (23.4)

25,316 (17.8)

1176 (10.0)

77 (21.8)

62 (16.6)

9 (12.2)

 One to four times a week

119,836 (52.4)

66,267 (46.5)

3711 (31.6)

172 (48.6)

147 (39.3)

24 (32.4)

 One to three times a month

23,582 (10.3)

17,695 (12.4)

1487 (12.6)

40 (11.2)

43 (11.5)

10 (13.5)

 Never or special occasions

31,846 (13.9)

33,272 (23.3)

5388 (45.8)

65 (18.4)

122 (32.6)

31 (41.9)

Multimorbidity, n (%)

 None

93,868 (41.0)

40,383 (28.4)

1068 (9.1)

87 (24.6)

65 (17.4)

6 (8.1)

 1

78,185 (34.2)

46,384 (32.5)

2357 (20.0)

119 (33.6)

106 (28.3)

7 (9.5)

 2–3

51,407 (22.5)

46,373 (32.5)

5371 (45.7)

133 (37.6)

156 (41.7)

36 (48.6)

 ≥ 4

5271 (2.3)

9410 (6.6)

2966 (25.2)

15 (4.2)

47 (12.6)

25 (33.8)

  1. The frailty phenotype was derived using an adaptation from the original derived by Fried et al. Participants were classified as frail if they fulfilled three or more criteria, pre-frail if they fulfilled one or two criteria, and robust if they did not fulfil any criteria at baseline
  2. SD standard deviation, n number