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Table 2 Risk of stroke, myocardial infarction, and both according to TyG index quartile

From: The triglyceride glucose index is a simple and low-cost marker associated with atherosclerotic cardiovascular disease: a population-based study

TyG index

Events (n)

Duration (person-years)

Incidence rate (per 1000 person-years)

Model 1, hazard ratio (95% CI)

Model 2, hazard ratio (95% CI)

Model 3, hazard ratio (95% CI)

Myocardial infarction and stroke

 Q1

26,773

11,447,594.33

2.33874

1 (ref.)

1 (ref.)

1(ref.)

 Q2

33,335

11,430,071.25

2.91643

1.247 (1.227, 1.267)

1.18 (1.161, 1.199)

1.085 (1.068, 1.103)

 Q3

39,119

11,416,557.3

3.42651

1.466 (1.443, 1.489)

1.338 (1.317, 1.359)

1.157 (1.138, 1.176)

 Q4

47,517

11,384,076.25

4.17399

1.786 (1.759, 1.813)

1.608 (1.584, 1.633)

1.282 (1.262, 1.304)

p for trend

   

< .0001

< .0001

< .0001

Myocardial infarction

 Q1

11,223

11,503,460.68

0.97562

1 (ref.)

1 (ref.)

1 (ref.)

 Q2

14,124

11,500,096.33

1.22816

1.257 (1.226, 1.289)

1.204 (1.174, 1.234)

1.092 (1.065, 1.12)

 Q3

16,618

11,499,511.73

1.4451

1.48 (1.444, 1.516)

1.379 (1.346, 1.412)

1.165 (1.137, 1.194)

 Q4

20,612

11,483,933.86

1.79486

1.837 (1.795, 1.88)

1.697 (1.658, 1.737)

1.312 (1.28, 1.345)

p for trend

   

< .0001

< .0001

< .0001

Stroke

 Q1

16,378

11,483,024.16

1.42628

1 (ref.)

1 (ref.)

1 (ref.)

 Q2

20,315

11,474,799.11

1.7704

1.242 (1.217, 1.268)

1.164 (1.14, 1.188)

1.080 (1.058, 1.103)

 Q3

23,806

11,469,602.92

2.07557

1.457 (1.428, 1.486)

1.306 (1.28, 1.333)

1.148 (1.125, 1.172)

 Q4

28,621

11,450,595.06

2.49952

1.754 (1.72, 1.788)

1.545 (1.515, 1.575)

1.260 (1.234, 1.287)

p for trend

   

< .0001

< .0001

< .0001

  1. Model 1: crude
  2. Model 2: adjusted for age and sex
  3. Model 3: adjusted for age, sex, smoking, alcohol consumption, regular physical activity, low socioeconomic status, body mass index, hypertension, total cholesterol level, hypertension medications, warfarin, and aspirin