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Table 1 Baseline characteristics of participants in the derivation and validation cohorts

From: Development and validation of a lifestyle-based model for colorectal cancer risk prediction: the LiFeCRC score

Characteristics Derivation cohort Validation cohort
All participants Men Women All participants Men Women
N 255,482 83,101 172,381 74,403 29,259 45,144
Age at recruitment, years, mean (SD) 51.4 (9.7) 52.3 (9.0) 51.0 (9.9) 49.7 (9.6) 50.7 (9.3) 49.0 (9.8)
Age range, years 19.5 to 70.0 19.5 to 70.0 20.0 to 70.0 19.9 to 70.0 20.1 to 69.2 19.9 to 70.0
BMI, kg/m2, mean (SD) 25.8 (4.3) 26.6 (3.6) 25.4 (4.5) 26.0 (4.2) 26.6 (3.6) 25.7 (4.5)
Waist, cm, mean (SD) 84.6 (12.9) 94.6 (10.0) 79.8 (11.3) 86.0 (12.5) 94.0 (10.2) 80.8 (11.0)
Height, cm, mean (SD) 165.8 (9.1) 174.3 (7.3) 161.7 (6.7) 167.3 (9.6) 175.5 (7.3) 162.1 (6.9)
Postmenopausal status, %    49.5    41.8
Ever use of hormone for menopause, %    26.0    23.8
Smoking status, %
 Smoker 23.5 31.3 19.7 27.0 32.3 23.5
 Former 27.4 36.2 23.1 27.8 37.3 21.6
 Never 49.1 32.4 57.2 45.3 30.4 54.9
Physical activity, %
 Inactive 19.1 29.4 14.2 18.3 25.3 13.7
 Moderately inactive 30.3 32.9 29.0 27.2 30.0 25.4
 Moderately active 40.2 29.3 45.5 43.5 33.7 49.9
 Active 10.3 8.5 11.2 11.0 11.0 11.0
Education, %
 None 5.9 4.9 6.3 3.1 2.4 3.6
 Primary school completed 27.0 30.6 25.2 29.2 24.8 32.1
 Technical school/professional school 22.4 22.7 22.3 31.1 29.8 31.9
 Secondary school 16.2 11.9 18.3 13.4 11.4 14.7
 University degree 24.6 27.4 23.3 23.0 31.5 17.5
 Not specified 4.0 2.5 4.7 0.2 0.2 0.3
Dietary intake, g/day, median (IQR)
 Alcohol 6.6 (1.1 to 17.1) 14.4 (5.0 to 32.3) 4.1 (0.6 to 11.9) 7.8 (1.5 to 19.7) 16.4 (6.7 to 32.9) 4.2 (0.6 to 11.8)
 Vegetables 196.9 (124.4 to 301.8) 179.7 (110.8 to 287.8) 204.9 (131.5 to 307.4) 130.0 (92.8 to 183.2) 124.0 (88.1 to 174.7) 133.9 (95.9 to 189.1)
 Fruits 215.1 (117.1 to 340.8) 176.6 (88.5 to 313.3) 232.7 (132.4 to 351.8) 161.0 (94.1 to 264.7) 127.4 (73.9 to 225.3) 186.0 (105.6 to 290.3)
 Dark bread 28.6 (0.0 to 91.8) 34.9 (0.0 to 112.5) 27.9 (0.0 to 87.8) 91.4 (15.0 to 150.2) 115.8 (49.3 to 179.6) 73.2 (8.0 to 128.0)
 Dairy products 283.0 (159.5 to 447.5) 257.3 (130.0 to 434.3) 295.2 (173.1 to 451.7) 265.1 (150.0 to 434.7) 256.8 (136.7 to 447.0) 270.2 (158.8 to 428.7)
 Red meat 38.2 (17.3 to 65.4) 49.7 (24.8 to 80.5) 33.8 (13.9 to 57.3) 44.8 (23.9 to 74.5) 61.9 (33.5 to 93.1) 36.9 (19.8 to 61.1)
 Poultry 16.1 (5.8 to 30.9) 16.4 (7.3 to 34.3) 15.8 (4.8 to 29.3) 13.2 (6.5 to 24.3) 14.6 (7.3 to 25.5) 12.4 (5.9 to 23.4)
 Processed meat 19.2 (6.4 to 37.9) 27.9 (10.8 to 51.9) 16.4 (5.4 to 31.8) 34.5 (17.9 to 59.6) 47.6 (27.4 to 76.7) 27.8 (14.6 to 48.7)
 Fish 21.4 (9.3 to 37.0) 24.3 (12.6 to 41.2) 19.7 (7.7 to 34.9) 16.1 (6.0 to 30.3) 17.6 (6.3 to 32.2) 15.3 (5.9 to 27.9)
 Sugar and confectionary 31.6 (16.3 to 55.2) 36.9 (19.2 to 65.0) 29.6 (15.2 to 51.0) 35.3 (18.7 to 60.0) 41.0 (21.7 to 70.3) 32.3 (17.1 to 54.1)
 Soft drinks 9.5 (0.0 to 85.7) 16.4 (0.0 to 100.0) 6.6 (0.0 to 74.3) 8.7 (0.0 to 85.7) 19.3 (0.0 to 118.7) 3.8 (0.0 to 66.0)
  1. BMI body mass index, IQR interquartile range, SD standard deviation