Table 3 Number (%) of participants reporting a symptom as among their three most troubling symptoms after gluten challenge according to peak reaction severity
From: Patient factors influencing acute gluten reactions and cytokine release in treated coeliac disease
Peak severity of global gastrointestinal symptoms (GloSS)‡ | Totalb | ||||||
|---|---|---|---|---|---|---|---|
Nonea | Very milda | Milda | Moderatea | Severea | Very severea | ||
Total patients | 8 (3) | 33 (11) | 65 (22) | 104 (35) | 54 (18) | 31 (11) | 295 (100) |
Nausea | 1 (13) | 5 (15) | 29 (45) | 54 (52) | 32 (60) | 21 (72) | 142 (49) |
Tiredness | 3 (38) | 16 (48) | 32 (50) | 50 (49) | 24 (45) | 3 (10) | 128 (44) |
Abdominal pain/cramps | 1 (13) | 8 (24) | 24 (38) | 48 (47) | 24 (45) | 13 (45) | 118 (41) |
Bloating | 0 | 15 (45) | 22 (52) | 43 (42) | 15 (28) | 1 (3) | 107 (37) |
Headache | 1 (13) | 14 (42) | 24 (38) | 44 (43) | 16 (30) | 4 (14) | 103 (36) |
Vomiting | 0 | 0 | 1 (2) | 13 (13) | 24 (45) | 26 (90) | 64 (22) |
Gas | 0 | 8 (24) | 25 (39) | 21 (20) | 6 (11) | 0 | 60 (21) |
Diarrhoea/loose stool | 0 | 1 (3) | 5 (8) | 12 (12) | 11 (21) | 14 (48) | 43 (15) |
None | 5 (63) | 1 (3) | 0 | 1 (1) | 0 | 0 | 7 (2) |
Others | 0 | 2 (6) | 3 (5) | 1 (1) | 0 | 0 | 6 (2) |