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Table 5 Difference in longitudinal BMI change from baseline (age 1) stratified by PCOS phenotype

From: Updated adolescent diagnostic criteria for polycystic ovary syndrome: impact on prevalence and longitudinal body mass index trajectories from birth to adulthood

  Original non-PCOS (n = 161) OA + HA (updated PCOS) (n = 37) HA + PCOM (n = 9) OA + PCOM (n = 20)
∆BMI 95% CI ∆BMI 95% CI p value* ∆BMI 95% CI p value# ∆BMI 95% CI p value$
Age 1
Age 2 − 1.31 − 2.14 to − 0.47 − 2.57 − 5.63 to 0.49 0.200 − 2.02 − 4.66 to 0.61 0.745 − 1.99 − 4.94 to 0.95 0.692
Age 3 − 0.93 − 1.49 to − 0.37 − 1.86 − 4.38 to 0.67 0.273 − 0.55 − 2.83 to 1.73 0.849 − 1.27 − 2.65 to 0.10 0.694
Age 5 − 1.21 − 1.72 to − 0.69 − 1.02 − 3.21 to 1.17 0.844 − 1.41 − 3.35 to 0.54 0.888 − 1.81 − 3.18 to 0.43 0.487
Age 8 − 0.18 − 0.70 to 0.34 0.32 − 1.81 to 2.45 0.531 0.37 − 1.57 to 2.31 0.704 − 1.17 − 2.57 to 0.23 0.263
Age 10 1.18 0.67 to 1.69 2.73 0.57 to 4.89 0.047 2.82 0.88 to 4.77 0.253 0.31 − 1.07 to 1.68 0.314
Age 14 4.24 3.73 to 4.75 7.51 5.38 to 9.64 < 0.001 5.69 3.75 to 7.64 0.312 3.61 2.24 to 4.99 0.471
Age 16 5.77 5.25 to 6.29 9.60 7.41 to 11.79 < 0.001 6.33 4.39 to 8.28 0.696 4.89 3.49 to 6.29 0.322
Age 20 6.85 6.33 to 7.37 10.20 7.97 to 12.42 < 0.001 6.95 5.00 to 8.89 0.946 5.41 4.01 to 6.81 0.097
Age 22 7.39 6.87 to 7.91 12.17 10.01 to 14.33 < 0.001 6.09 4.14 to 8.03 0.365 6.74 5.32 to 8.13 0.436
  1. Models were generated using generalized estimating equations and adjusted for age of menarche, family income at age 14, smoking status at age 22, and marital status at age 22
  2. ∆BMI mean BMI change, CI confidence interval, HA hyperandrogenism, OA oligo-anovulation, PCOM polycystic ovary morphology, PCOS polycystic ovary syndrome
  3. *p value for the interaction term phenotype OA + HA by age, comparing OA + HA with original non-PCOS
  4. #p value for the interaction term phenotype HA + PCOM by age, comparing HA + PCOM with original non-PCOS
  5. $p value for the interaction term phenotype OA + PCOM by age, comparing OA + PCOM with original non-PCOS