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Table 2 Relative risk of indicators of placental insufficiency when a 20–36-week EFW and AC growth velocity cut-off of < − 30 centiles is used to dichotomise the cohort

From: Reduced growth velocity from the mid-trimester is associated with placental insufficiency in fetuses born at a normal birthweight

  Growth parameter Low growth velocity n (%) Growth velocity not low n (%) RR (95% CI) if low 20–36-week growth velocity of < − 30 centiles P
CPR < 5th centile [12] EFW 11/65 (16.9) 18/237 (7.6) 2.23 (1.11–4.36) 0.03
Umbilical artery pH < 7.15 at birth EFW 9/48 (18.8) 15/190 (7.9) 2.38 (1.11–4.93) 0.03
AC 5/18 (27.8) 19/220 (8.6) 3.22 (1.32–6.93) 0.02
ADP low body fat percentage [13] AC 1/9 (11.1) 11/127 (8.7) 1.28 (0.22–5.87) 0.58
Placental weight < 10th centile [21] EFW 27/61 (44.3) 36/216 (16.7) 2.66 (1.75–3.96) < 0.0001
AC 10/22 (45.5) 53/255 (20.8) 2.19 (1.24–3.44) 0.01
  1. RR relative risk, CI confidence interval, EFW estimated fetal weight, AC abdominal circumference, CPR cerebroplacental ratio, ADP air displacement plethysmography