Development and validation of the VitaL CLASS score to predict mortality in stage IV solid cancer patients with septic shock in the emergency department: a multi-center, prospective cohort study

Table 4 The new prognostic scoring system named VitaL CLASS score (vital signs-lung cancer-lactate-albumin in septic shock) predicting for 28-day mortality

Risk factor	Category	Bias-corrected regression coefficient	Points*
Lung cancer	No	0	0
Lung cancer	Yes	0.617	1
Vital signs at ED admission
Respiratory rate	< 22/min	0	0
Respiratory rate	≥ 22/min	0.891	1
Body temperature	≥ 38.0 °C	0	0
Body temperature	< 38.0 °C	1.016	2
Mentation	Alert	0	0
Mentation	Alteration	0.645	1
Laboratory values
Albumin	≥ 2.8 g/dL	0	0
Albumin	< 2.8 g/dL	0.864	1
Lactic acid, mmol/L	< 4.0	0	0
	4.0–7.9	0.446	1
	≥ 8.0	1.228	2

ED emergency department
Total score ranges 0–8
*Risk points were obtained by bias-corrected regression coefficients and reference values in each category. Each risk point was rescaled to designate the point of lung cancer as 1

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