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Table 5 The C-indices for testing of the VitaL CLASS score and other pre-existing scoring systems

From: Development and validation of the VitaL CLASS score to predict mortality in stage IV solid cancer patients with septic shock in the emergency department: a multi-center, prospective cohort study

Scoring system

Development set

Validation set

AIC

C-index (95% CI)

p value

AIC

C-index (95% CI)

p value

VitaL CLASS score

1287.4

0.808 (0.772–0.845)

Reference

1299.1

0.736 (0.694–0.778)

Reference

SOFA score

1362.0

0.713 (0.664–0.762)

0.001

1347.2

0.656 (0.603–0.708)

0.01

APACHE II score

1370.3

0.692 (0.643–0.741)

< 0.001

1329.1

0.682 (0.633–0.731)

0.08

Quick SOFA score

1419.2

0.614 (0.565–0.663)

< 0.001

1380.4

0.552 (0.502–0.601)

< 0.001

NEWS

1399.2

0.669 (0.617–0.720)

< 0.001

1379.3

0.561 (0.509–0.613)

< 0.001

MEWS

1435.5

0.554 (0.501–0.607)

< 0.001

1383.6

0.486 (0.433–0.540)

< 0.001

  1. AIC Akaike information criterion, APACHE Acute Physiology and Chronic Health Evaluation, CI confidence interval, MEWS Modified Early Warning Score, NEWS National Early Warning Score, SOFA Sequential Organ Failure Assessment, VitaL CLASS vital signs-lung cancer-lactate-albumin in septic shock
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BMC Medicine

ISSN: 1741-7015

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