Fig. 3
Association between body mass index and the risk of 10 cancer types in never smokers, allowing for non-linear effects, with 99% CIs. Notes: (1) The reference BMI for these plots was 22 kg/m2. Separate models were fitted for each cancer type and adjusted for alcohol intake, nationality, the MEDEA deprivation index, type 2 diabetes, and had sex and age (5-year categories) in the strata statement. Each model had a restricted cubic spline for BMI with 3 knots placed at 21, 26, and 34 kg/m2 except for head and neck, bronchus and lung, and corpus uteri that had 5 knots placed at 19, 23, 26, 29, and 37 kg/m2. (2) Lung includes trachea and bronchus tumors. (3) The association for corpus uteri cancer was only computed in women, for breast post-menopausal only in post-menopausal women, and for prostate cancer only in men. (4) All models have a scale up to a HR of 3, except for corpus uteri and Hodgkin lymphoma. Abbreviations: BMI, body mass index; CI, confidence interval; HR, hazard ratio; KG, kilograms; M, meters