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Table 1 Baseline characteristics of the study participants included in the analyses of the first objective (dataset 1) by body mass index categories and of the second objective (dataset 2)

From: Body mass index and waist circumference in relation to the risk of 26 types of cancer: a prospective cohort study of 3.5 million adults in Spain

 

Dataset 1, N (%)

Dataset 2, N (%)

 

Under and normal weight (BMI < 25)

Overweight (BMI ≥ 25 and < 30)

Obese (BMI ≥ 30)

BMI total

WC total

Characteristic

1,436,991 (39.3)

1,326,642 (36.3)

894,784 (24.4)

3,658,417 (100)

291,305 (100)

Follow-up (in years)a,b

7.7 (4.4–10.6)

8.5 (5.0–11.3)

9.1 (5.6–11.8)

8.3 (4.9–11.2)

9.9 (6.9–11.9)

Visits to health centerb,c

5 (3–9)

7 (4–12)

8 (5–14)

6 (3–11)

10 (6–16)

BMIb

22.5 (20.8–23.8)

27.3 (26.1–28.5)

32.9 (31.2–35.6)

26.3 (23.2–29.9)

29.0 (25.9–32.5)

WCb

100 (91–108)

Age (in years)b,d

36 (27–50)

51 (37–65)

55 (42–66)

46 (32–61)

59 (46–71)

Sex

 Men

527,253 (36.7)

707,939 (53.4)

394,948 (44.1)

1,630,140 (44.6)

137,298 (47.1)

 Women

909,738 (63.3)

618,703 (46.6)

499,836 (55.9)

2,028,277 (55.4)

154,007 (52.9)

MEDEA deprivation indexe

 Quintile 1

226,165 (15.7)

180,162 (13.6)

98,899 (11.0)

505,226 (13.8)

32,542 (11.2)

 Quintile 2

208,133 (14.5)

189,510 (14.3)

119,236 (13.3)

516,879 (14.2)

39,826 (13.7)

 Quintile 3

198,978 (13.9)

192,240 (14.5)

131,763 (14.7)

522,981 (14.3)

40,019 (13.7)

 Quintile 4

193,565 (13.5)

195,463 (14.7)

142,024 (15.9)

531,052 (14.5)

41,767 (14.3)

 Quintile 5

190,155 (13.2)

185,886 (14.0)

144,632 (16.2)

520,673 (14.2)

34,249 (11.8)

 Rural

263,435 (18.3)

251,378 (18.9)

169,075 (18.9)

683,888 (18.7)

73,535 (25.2)

 Missing

156,560 (10.9)

132,003 (10.0)

89,155 (10.0)

377,718 (10.3)

29,367 (10.1)

Nationality (geographic region)

 Spain

1,216,424 (84.6)

1,169,166 (88.1)

804,483 (89.9)

3,190,073 (87.2)

271,950 (93,3)

 Europe (non-Spanish)

68,689 (4.8)

36,592 (2.8)

22,475 (2.5)

127,756 (3.5)

5560 (1.9)

 Africa

15,968 (1.1)

13,208 (1.0)

6379 (0.7)

34,655 (1.0)

1019 (0.4)

 America

75,117 (5.2)

63,293 (4.8)

37,867 (4.2)

176,277 (4.8)

7310 (2.5)

 Asia

61,693 (4.3)

44,383 (3.3)

23,580 (2.7)

129,656 (3.5)

5466 (1.9)

Smoking status

 Never

674,872 (46.9)

688,304 (51.9)

487,643 (54.5)

1,850,819 (50.6)

174,775 (60.0)

 Former

113,105 (7.9)

154,969 (11.7)

106,333 (11.9)

374,407 (10.2)

33,958 (11.6)

 Current

438,103 (30.5)

308,376 (23.2)

177,332 (19.8)

923,811 (25.3)

58,468 (20.1)

 Missing

210,911 (14.7)

174,993 (13.2)

123,476 (13.8)

509,380 (13.9)

24,104 (8.3)

Alcohol intake

 None

541,451 (37.7)

464,399 (35.0)

315,211 (35.2)

1,321,061 (36.1)

107,230 (36.8)

 Low

340,721 (23.7)

325,238 (24.5)

173,382 (19.4)

839,341 (22.9)

60,568 (20.8)

 High

25,114 (1.7)

28,074 (2.1)

19,043 (2.1)

72,231 (2.0)

7077 (2.4)

 Missing

529,705 (36.9)

508,931 (38.4)

387,148 (43.3)

1,425,784 (39.0)

116,430 (40.0)

Type 2 diabetes

34,847 (2.4)

109,302 (8.2)

123,313 (13.8)

267,426 (7.3)

50,269 (17.3)

Cause of end of follow-up

 End of study

1,170,596 (81.5)

1,037,513 (78.2)

683,190 (76.4)

2,891,299 (79.0)

207,329 (71.2)

 Cancerf

47,609 (3.3)

87,344 (6.6)

67,875 (7.6)

202,828 (5.6)

27,837 (9.5)

 Death

51,777 (3.6)

82,920 (6.2)

70,090 (7.8)

204,787 (5.6)

33,702 (11.6)

 Transferred-out

167,009 (11.6)

118,865 (9.0)

73,629 (8.2)

359,503 (9.8)

22,437 (7.7)

  1. BMI body mass index, MEDEA “Mortalidad en áreas pequeñas Españolas y Desigualdades Socioeconómicas y Ambientales”, WC waist circumference
  2. aParticipants were followed from the study index date until cancer diagnosis, death, transferal out of the SIDIAP, or until the end of the study period (December 31, 2018)
  3. bMedian (interquartile range)
  4. cVisits to general practitioners and nurses during the year of BMI assessment
  5. dAt baseline
  6. eQuintile 1 represents the least deprived and quintile 5 represents the most deprived. Rural was included as a category since the index cannot be calculated for people living in rural areas
  7. fAny, excl. non-melanoma skin cancer