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Table 1 Baseline characteristics of the study participants included in the analyses of the first objective (dataset 1) by body mass index categories and of the second objective (dataset 2)

From: Body mass index and waist circumference in relation to the risk of 26 types of cancer: a prospective cohort study of 3.5 million adults in Spain

  Dataset 1, N (%) Dataset 2, N (%)
  Under and normal weight (BMI < 25) Overweight (BMI ≥ 25 and < 30) Obese (BMI ≥ 30) BMI total WC total
Characteristic 1,436,991 (39.3) 1,326,642 (36.3) 894,784 (24.4) 3,658,417 (100) 291,305 (100)
Follow-up (in years)a,b 7.7 (4.4–10.6) 8.5 (5.0–11.3) 9.1 (5.6–11.8) 8.3 (4.9–11.2) 9.9 (6.9–11.9)
Visits to health centerb,c 5 (3–9) 7 (4–12) 8 (5–14) 6 (3–11) 10 (6–16)
BMIb 22.5 (20.8–23.8) 27.3 (26.1–28.5) 32.9 (31.2–35.6) 26.3 (23.2–29.9) 29.0 (25.9–32.5)
WCb 100 (91–108)
Age (in years)b,d 36 (27–50) 51 (37–65) 55 (42–66) 46 (32–61) 59 (46–71)
Sex
 Men 527,253 (36.7) 707,939 (53.4) 394,948 (44.1) 1,630,140 (44.6) 137,298 (47.1)
 Women 909,738 (63.3) 618,703 (46.6) 499,836 (55.9) 2,028,277 (55.4) 154,007 (52.9)
MEDEA deprivation indexe
 Quintile 1 226,165 (15.7) 180,162 (13.6) 98,899 (11.0) 505,226 (13.8) 32,542 (11.2)
 Quintile 2 208,133 (14.5) 189,510 (14.3) 119,236 (13.3) 516,879 (14.2) 39,826 (13.7)
 Quintile 3 198,978 (13.9) 192,240 (14.5) 131,763 (14.7) 522,981 (14.3) 40,019 (13.7)
 Quintile 4 193,565 (13.5) 195,463 (14.7) 142,024 (15.9) 531,052 (14.5) 41,767 (14.3)
 Quintile 5 190,155 (13.2) 185,886 (14.0) 144,632 (16.2) 520,673 (14.2) 34,249 (11.8)
 Rural 263,435 (18.3) 251,378 (18.9) 169,075 (18.9) 683,888 (18.7) 73,535 (25.2)
 Missing 156,560 (10.9) 132,003 (10.0) 89,155 (10.0) 377,718 (10.3) 29,367 (10.1)
Nationality (geographic region)
 Spain 1,216,424 (84.6) 1,169,166 (88.1) 804,483 (89.9) 3,190,073 (87.2) 271,950 (93,3)
 Europe (non-Spanish) 68,689 (4.8) 36,592 (2.8) 22,475 (2.5) 127,756 (3.5) 5560 (1.9)
 Africa 15,968 (1.1) 13,208 (1.0) 6379 (0.7) 34,655 (1.0) 1019 (0.4)
 America 75,117 (5.2) 63,293 (4.8) 37,867 (4.2) 176,277 (4.8) 7310 (2.5)
 Asia 61,693 (4.3) 44,383 (3.3) 23,580 (2.7) 129,656 (3.5) 5466 (1.9)
Smoking status
 Never 674,872 (46.9) 688,304 (51.9) 487,643 (54.5) 1,850,819 (50.6) 174,775 (60.0)
 Former 113,105 (7.9) 154,969 (11.7) 106,333 (11.9) 374,407 (10.2) 33,958 (11.6)
 Current 438,103 (30.5) 308,376 (23.2) 177,332 (19.8) 923,811 (25.3) 58,468 (20.1)
 Missing 210,911 (14.7) 174,993 (13.2) 123,476 (13.8) 509,380 (13.9) 24,104 (8.3)
Alcohol intake
 None 541,451 (37.7) 464,399 (35.0) 315,211 (35.2) 1,321,061 (36.1) 107,230 (36.8)
 Low 340,721 (23.7) 325,238 (24.5) 173,382 (19.4) 839,341 (22.9) 60,568 (20.8)
 High 25,114 (1.7) 28,074 (2.1) 19,043 (2.1) 72,231 (2.0) 7077 (2.4)
 Missing 529,705 (36.9) 508,931 (38.4) 387,148 (43.3) 1,425,784 (39.0) 116,430 (40.0)
Type 2 diabetes 34,847 (2.4) 109,302 (8.2) 123,313 (13.8) 267,426 (7.3) 50,269 (17.3)
Cause of end of follow-up
 End of study 1,170,596 (81.5) 1,037,513 (78.2) 683,190 (76.4) 2,891,299 (79.0) 207,329 (71.2)
 Cancerf 47,609 (3.3) 87,344 (6.6) 67,875 (7.6) 202,828 (5.6) 27,837 (9.5)
 Death 51,777 (3.6) 82,920 (6.2) 70,090 (7.8) 204,787 (5.6) 33,702 (11.6)
 Transferred-out 167,009 (11.6) 118,865 (9.0) 73,629 (8.2) 359,503 (9.8) 22,437 (7.7)
  1. BMI body mass index, MEDEA “Mortalidad en áreas pequeñas Españolas y Desigualdades Socioeconómicas y Ambientales”, WC waist circumference
  2. aParticipants were followed from the study index date until cancer diagnosis, death, transferal out of the SIDIAP, or until the end of the study period (December 31, 2018)
  3. bMedian (interquartile range)
  4. cVisits to general practitioners and nurses during the year of BMI assessment
  5. dAt baseline
  6. eQuintile 1 represents the least deprived and quintile 5 represents the most deprived. Rural was included as a category since the index cannot be calculated for people living in rural areas
  7. fAny, excl. non-melanoma skin cancer