| |
Low-burden
|
Metabolic-vascular
|
Ischemic
|
Anemia
|
Metabolic
|
Overall
|
|---|
| |
N = 83,577
|
N = 73,284
|
N = 83,283
|
N = 14,959
|
N = 63,281
|
N = 318,030
|
|
Deaths, n (%)
|
18,497 (22.2%)
|
17,943 (24.5%)
|
32,709 (39.3%)
|
4615 (30.9%)
|
8774 (13.9%)
|
82,538 (26%)
|
|
Person-months
|
3,666,146
|
2,270,448
|
3,246,368
|
545,985
|
2,334,907
|
12,063,855
|
|
Deaths per 1000 person-months (95% CI)
|
5.05 (4.97–5.12)
|
7.9 (7.8–8.02)
|
10.08 (9.96–10.18)
|
8.45 (8.21–8.70)
|
3.76 (3.68–3.84)
|
6.84 (6.80–6.89)
|
|
Model 1a
|
N = 77,325
|
N = 68,414
|
N = 77,425
|
N = 13,850
|
N = 58,635
|
N = 295,649
|
|
Deaths, n (%)
|
17,291 (22.4%)
|
16,414 (24.7%)
|
30,510 (39.4%)
|
4325 (31.2%)
|
8251 (14.1%)
|
77,276 (26.1%)
|
|
Adjusted HRa (95% CI)
|
1.00 (Ref)
|
1.87 (1.74–2.01)
|
1.24 (1.16–1.33)
|
1.46 (1.30–1.64)
|
1.18 (1.09–1.29)
| |
|
Model 2b
|
2707
|
3267
|
3265
|
247
|
2483
|
N = 12,091
|
|
Deaths, n (%)
|
510 (20.1%)
|
755 (24.6%)
|
1166 (38%)
|
98 (28.3%)
|
281 (12.1%)
|
3478 (28.8%)
|
|
Adjusted HRb (95% CI)
|
1.00 (Ref)
|
1.60 (1.44, 1.79)
|
1.62 (1.47, 1.80)
|
1.60 (1.30, 1.96)
|
0.96 (0.84, 1.10)
| |
- Abbreviations: CI confidence interval, HR hazard ratio, ref. reference
- aAdjusted for age, sex, race, education, medical insurance status, whether diagnosis was gained inpatient or in outpatient and HF medications; time-varying coefficient model; excludes patients with missing data on race (21,557) and education (2097)
- bAdjusted for age, sex, race, education, medical insurance status, whether diagnosis was gained inpatient or in outpatient, HF medications, ejection fraction, smoking status; proportional hazards met; excludes patients with missing data on race (21,557), education (2097), ejection fraction (304,477), and smoking status (282,333)
