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Fig. 2 | BMC Medicine

Fig. 2

From: rs1990622 variant associates with Alzheimer’s disease and regulates TMEM106B expression in human brain tissues

Fig. 2

Colocalization analysis of genetic variants associated with TMEM106B expression in GTEx cerebellum and AD risk. Created using locuscomparer R package. Coloc PP0 = 0.031, PP1 = 0.002, PP2 = 0.735, PP3 = 0.037, and PP4 = 0.196. The eQTLs dataset is from GTEx cerebellum (n = 209). The AD GWAS dataset is from the IGAP including 21,982 AD and 41,944 cognitively normal controls

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BMC Medicine

ISSN: 1741-7015

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