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Table 2 Association between rs1990622 variant T allele and AD

From: rs1990622 variant associates with Alzheimer’s disease and regulates TMEM106B expression in human brain tissues

Dataset

Disease

Beta

SE

P value

IGAP

AD

0.040

0.014

5.42E−03

UK Biobank

AD

0.025

0.010

1.20E−02

UK Biobank

AD in females

0.043

0.012

5.74E−04

UK Biobank

AD in males

0.008

0.017

6.48E01

  1. SE standard error. Beta is the regression coefficient based on the effect allele. Beta > 0 and beta < 0 mean that this effect allele could increase and reduce AD risk, respectively. The statistically significant association is defined to be P < 0.05