ID | Study | N | Period | Study type | Site | Median follow-up (months) | Primary outcomes |
---|---|---|---|---|---|---|---|
1 | BIOSTAT-index | 2516 | 2010–2012 | Cohort | 69 centers in 11 European countries | 21 | Time to composite death or unscheduled hospitalizations for HF |
2 | BIOSTAT-validation | 1738 | 2010–2014 | Cohort | 6 centers in Scotland | 21 | Time to composite death or unscheduled hospitalizations for HF |
3 | TRIUMPH | 475 | 2009–2012 | Cohort | 14 centers in the Netherlands | 10.8 | All-cause mortality and readmission for HF |
4 | COACH | 1023 | 2002–2007 | RCT | 17 centers in the Netherlands | 18.4 | Time to death or rehospitalization because of HF |