|
Variables
|
Transformation
|
Coef (SE)
|
HR (95% CI)
|
Pinteraction
|
|---|
|
Age, year
| |
0.023 (0.004)
|
1.02 (1.02–1.03)
| |
|
COPD
| |
0.298 (0.087)
|
1.35 (1.14–1.60)
| |
|
NYHA class III
| |
0.360 (0.124)
|
1.43 (1.12–1.83)
| |
|
NYHA class IV
| |
0.298 (0.133)
|
1.35 (1.04–1.75)
| |
|
Hemoglobin, mmol/L
| |
− 0.164 (0.034)
|
0.85 (0.79–0.91)
| |
|
Sodium, mmol/L
| |
− 0.032 (0.009)
|
0.97 (0.95–0.99)
| |
|
BUN, mmol/L
|
= log2(x*)
|
0.335 (0.065)
|
1.40 (1.23–1.59)
| |
|
NT-proBNP, ng/L
|
= log2(x)
|
0.294 (0.035)
|
1.34 (1.25–1.44)
| |
|
SBP (HFrEF), mmHg
|
= min(x,130)†
|
− 0.029 (0.003)
|
0.97 (0.96–0.98)
|
< .001
|
|
SBP (HFmrEF), mmHg
|
= min(x,130)
|
− 0.009 (0.008)
|
0.99 (0.98–1.01)
| |
|
SBP (HFpEF), mmHg
|
= min(x,130)
|
− 0.006 (0.007)
|
0.99 (0.98–1.01)
| |
|
Creatinine (HFrEF), μmol/L
|
= log2(x)
|
0.037 (0.100)
|
1.04 (0.85–1.26)
|
.010
|
|
Creatinine (HFmrEF), μmol/L
|
= log2(x)
|
− 0.367 (0.140)
|
0.69 (0.53–0.91)
| |
|
Creatinine (HFpEF), μmol/L
|
= log2(x)
|
− 0.209 (0.150)
|
0.81 (0.54–1.19)
| |
|
MI (HFrEF)
| |
0.430 (0.097)
|
1.54 (1.27–1.86)
|
.001
|
|
MI (HFmrEF)
| |
− 0.032 (0.188)
|
0.97 (0.67–1.40)
| |
|
MI (HFpEF)
| |
− 0.216 (0.201)
|
0.79 (0.53–1.17)
| |
|
Diabetes (HFrEF)
| |
0.265 (0.101)
|
1.30 (1.07–1.59)
|
.041
|
|
Diabetes (HFmrEF)
| |
− 0.176 (0.202)
|
0.84 (0.56–1.25)
| |
|
Diabetes (HFpEF)
| |
− 0.077 (0.190)
|
0.93 (0.64–1.34)
| |
- *x stands for original value
- †The SBP has a linear trend up to 130 mmHg, while above 130 mmHg the risk is constant. Therefore, we truncated SBP at 130 mmHg
