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Table 3 Results from multivariable Cox regression stratified by study cohort and HF subtype

From: A heart failure phenotype stratified model for predicting 1-year mortality in patients admitted with acute heart failure: results from an individual participant data meta-analysis of four prospective European cohorts

Variables Transformation Coef (SE) HR (95% CI) Pinteraction
Age, year   0.023 (0.004) 1.02 (1.02–1.03)  
COPD   0.298 (0.087) 1.35 (1.14–1.60)  
NYHA class III   0.360 (0.124) 1.43 (1.12–1.83)  
NYHA class IV   0.298 (0.133) 1.35 (1.04–1.75)  
Hemoglobin, mmol/L   − 0.164 (0.034) 0.85 (0.79–0.91)  
Sodium, mmol/L   − 0.032 (0.009) 0.97 (0.95–0.99)  
BUN, mmol/L = log2(x*) 0.335 (0.065) 1.40 (1.23–1.59)  
NT-proBNP, ng/L = log2(x) 0.294 (0.035) 1.34 (1.25–1.44)  
SBP (HFrEF), mmHg = min(x,130) − 0.029 (0.003) 0.97 (0.96–0.98) < .001
SBP (HFmrEF), mmHg = min(x,130) − 0.009 (0.008) 0.99 (0.98–1.01)  
SBP (HFpEF), mmHg = min(x,130) − 0.006 (0.007) 0.99 (0.98–1.01)  
Creatinine (HFrEF), μmol/L = log2(x) 0.037 (0.100) 1.04 (0.85–1.26) .010
Creatinine (HFmrEF), μmol/L = log2(x) − 0.367 (0.140) 0.69 (0.53–0.91)  
Creatinine (HFpEF), μmol/L = log2(x) − 0.209 (0.150) 0.81 (0.54–1.19)  
MI (HFrEF)   0.430 (0.097) 1.54 (1.27–1.86) .001
MI (HFmrEF)   − 0.032 (0.188) 0.97 (0.67–1.40)  
MI (HFpEF)   − 0.216 (0.201) 0.79 (0.53–1.17)  
Diabetes (HFrEF)   0.265 (0.101) 1.30 (1.07–1.59) .041
Diabetes (HFmrEF)   − 0.176 (0.202) 0.84 (0.56–1.25)  
Diabetes (HFpEF)   − 0.077 (0.190) 0.93 (0.64–1.34)  
  1. *x stands for original value
  2. The SBP has a linear trend up to 130 mmHg, while above 130 mmHg the risk is constant. Therefore, we truncated SBP at 130 mmHg