Variablea | Non-polyp | Conventional adenoma | Serrated polyp |
---|---|---|---|
No. of participants | 4576 | 535 | 402 |
Age at blood draw, years | 58.9 (6.1) | 59.4 (5.8) | 57.5 (6.1) |
White, % | 99 | 99 | 99 |
Height, cm | 164.0 (6.1) | 164.6 (5.9) | 164.4 (5.0) |
Body mass indexb, kg/m2 | 25.3 (4.5) | 25.9 (4.0) | 26.1 (4.1) |
Family history of colorectal cancer, % | 27 | 34 | 29 |
Pack-year of smoking | 11.7 (18.0) | 15.1 (18.8) | 17.8 (18.5) |
 Never, % | 46 | 44 | 34 |
 Past, % | 44 | 43 | 47 |
 Current, % | 10 | 14 | 20 |
Alcohol intakeb, g/day | 6.1 (9.6) | 6.3 (8.5) | 6.4 (8.8) |
Physical activityb, c, MET-hours/week | 19.1 (19.7) | 18.7 (19.3) | 17.7 (16.5) |
AHEI dietary scoreb | 54.7 (10.2) | 53.4 (9.1) | 53.3 (8.9) |
Regular aspirin used, % | 52 | 53 | 49 |
Biomarkere | |||
 Estrone (pg/ml) | 24.40 (17.10–35.19) | 25.23 (19.11–37.22) | 25.31 (18.47–38.71) |
 Total estradiol (pg/ml) | 5.79 (4.06–9.42) | 6.02 (4.39–10.58) | 6.64 (4.33–11.38) |
 Free estradiol (pg/ml) | 0.08 (0.05–0.13) | 0.09 (0.05–0.15) | 0.09 (0.05–0.15) |
 Total testosterone (ng/dl) | 18.70 (13.47–25.76) | 18.22 (12.93–25.07) | 18.09 (13.27–25.85) |
 Free testosterone (ng/dl) | 0.13 (0.08–0.20) | 0.14 (0.10–0.23) | 0.14 (0.10–0.22) |
 SHBG (nmol/L) | 71.72 (47.57–113.38) | 60.70 (40.90–92.75) | 60.21 (41.12–93.69) |
 Total estradiol (pg/ml)/total testosterone (pg/ml) | 0.03 (0.02–0.05) | 0.03 (0.02–0.06) | 0.04 (0.02–0.06) |