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Table 2 Characteristics of the propensity-matched cohorts of antibiotic users matching each of the different quintiles of prior antibiotic use to the lowest quintile

From: The effectiveness of frequent antibiotic use in reducing the risk of infection-related hospital admissions: results from two large population-based cohorts

 Matched quintile of prior antibiotic use
Reference (lowest)LowReference (lowest)MiddleReference (lowest)HighReference (lowest)Highest
CPRD
 Total N antibiotic prescriptions623,627623,627825,352825,352690,334690,334438,474438,474
 Age (mean)43.443.344.344.245.945.750.950.7
 Women (%)398,289 (63.9%)397,113 (63.7%)548,995 (66.5%)547,199 (66.3%)477,977 (69.2%)476,765 (69.1%)315,692 (72%)315,586 (72%)
 Comorbidity score (%)        
  Lowest (score 0)399,315 (64.0%)399,407 (64.0%)503,555 (61.0%)503,782 (61.0%)390,999 (56.6%)392,619 (56.9%)207,908 (47.4%)209,284 (47.7%)
  Low (scores 1–2)180,224 (28.9%)179,917 (28.9%)255,728 (31.0%)255,218 (30.9%)232,981 (33.7%)231,525 (33.5%)170,068 (38.8%)169,353 (38.6%)
  Middle (scores 3–4)33,581 (5.4%)33,681 (5.4%)50,506 (6.1%)50,647 (6.1%)50,596 (7.3%)50,269 (7.3%)45,536 (10.4%)45,106 (10.3%)
  High (scores 5–6)7633 (1.2%)7697 (1.2%)11,400 (1.4%)11,515 (1.4%)11,583 (1.7%)11,696 (1.7%)11,042 (2.5%)10,856 (2.5%)
  Highest (score 7+)2874 (0.5%)2925 (0.5%)4163 (0.5%)4190 (0.5%)4175 (0.6%)4225 (0.6%)3920 (0.9%)3875 (0.9%)
SAIL
N antibiotic prescriptions (total)246,887246,887159,261159,261141,620141,620102,947102,947
 Age (mean)36.136.036.936.638.638.343.843.4
 Women (%)149,856 (60.7%)149,799 (60.7%)102,248 (64.2%)101,854 (64%)92,545 (65.3%)92,484 (65.3%)68,444 (66.5%)68,816 (66.8%)
 Comorbidity score (%)        
  Lowest202,665 (82.1%)202,679 (82.1%)123,976 (77.8%)124,428 (78.1%)105,998 (74.8%)106,549 (75.2%)70,005 (68.0%)70,564 (68.5%)
  Low33,020 (13.4%)33,000 (13.4%)25,466 (16.0%)25,193 (15.8%)25,397 (17.9%)25,004 (17.7%)22,815 (22.2%)22,407 (21.8%)
  Middle8473 (3.4%)8493 (3.4%)7339 (4.6%)7177 (4.5%)7660 (5.4%)7498 (5.3%)7591 (7.4%)7490 (7.3%)
  High2005 (0.8%)2015 (0.8%)1819 (1.1%)1804 (1.1%)1887 (1.3%)1914 (1.4%)1881 (1.8%)1850 (1.8%)
  Highest724 (0.3%)700 (0.3%)661 (0.4%)659 (0.4%)678 (0.5%)655 (0.5%)655 (0.6%)636 (0.6%)