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Table 4 IRRs of infection-related hospital admissions in months 3–6 after stratified by the level of propensity and quintile of prior antibiotic use

From: The effectiveness of frequent antibiotic use in reducing the risk of infection-related hospital admissions: results from two large population-based cohorts

 Propensity for lowest prior antibiotic use
LowMiddleHighLowMiddleHigh
% in groups#% in groups#% in groups#IRR (95% CI)&IRR (95% CI)&IRR (95% CI)&
Quintiles of prior antibiotic use
 CPRD
  Low vs lowest41.4% vs 29.4%33.5% vs 32.8%25.1% vs 37.8%1.21 (1.02–1.45)1.34 (1.00–1.79)1.15 (0.75–1.75)
  Middle vs lowest45.8% vs 25.4%33.4% vs 32.7%20.8% vs 41.9%1.38 (1.18–1.61)1.38 (1.09–1.75)1.33 (0.91–1.94)
  High vs lowest53.7% vs 21.3%32.5% vs 33.3%13.8% vs 45.4%1.75 (1.48–2.06)1.74 (1.38–2.19)2.52 (1.45–4.37)
  Highest vs lowest69.1% vs 16.6%25.7% vs 36.3%5.2% vs 47.1%2.17 (1.79–2.64)2.88 (2.04–4.07)5.72 (2.08–15.76)
 SAIL
  Low vs lowest41.7% vs 27.7%33.5% vs 32.6%24.8% vs 39.7%1.22 (1.06–1.41)1.42 (1.19–1.69)1.56 (1.18–2.07)
  Middle vs lowest50.5% vs 25.3%32.3% vs 33.4%17.2% vs 41.4%1.50 (1.29–1.74)1.83 (1.44–2.34)1.82 (1.28–2.59)
  High vs lowest57.5% vs 21.5%30.5% vs 34.3%12.0% vs 44.2%1.72 (1.47–2.02)2.62 (2.12–3.24)3.67 (2.51–5.35)
  Highest vs lowest69.3% vs 15.8%25.2% vs 37.1%5.6% vs 47.2%2.13 (1.74–2.61)3.27 (2.60–4.12)3.01 (1.69–5.37)
  1. #Unmatched cohorts
  2. &Propensity-matched cohorts