|
Sex, % women
|
27,419 (52.1)
|
2256 (53.0)
|
2654 (54.9)
|
5507 (51.4)
|
6096 (50.3)
|
5283 (51.8)
|
3294 (53.3)
|
2329 (53.8)
|
< 0.01
|
|
Age, (years), mean ± SD
|
72.0 ± 11.9
|
71.7 ± 13.3
|
71.9 ± 13.6
|
70.7 ± 12.5
|
71.8 ± 11.7
|
72.6 ± 11.1
|
72.9 ± 10.7
|
73.1 ± 10.6
|
< 0.01
|
|
Smoking (%)
|
|
Current
|
9847 (18.7)
|
877 (20.6)
|
911 (18.8)
|
2252 (21.0)
|
2401 (19.8)
|
1822 (17.9)
|
948 (15.4)
|
636 (14.7)
| |
|
Former
|
16,458 (31.3)
|
1186 (27.9)
|
1349 (27.9)
|
3144 (29.4)
|
3855 (31.8)
|
3304 (32.4)
|
2121 (34.3)
|
1499 (34.6)
| |
|
Never
|
24,507 (46.6)
|
1997 (46.9)
|
2364 (48.9)
|
4930 (46.1)
|
5442 (44.9)
|
4767 (46.8)
|
2929 (47.4)
|
2078 (48.0)
| |
|
Missing
|
1807 (3.4)
|
199 (4.7)
|
213 (4.4)
|
379 (3.5)
|
414 (3.4)
|
304 (3.0)
|
179 (2.9)
|
119 (2.8)
| |
|
Alcohol (%)
|
|
Current
|
26,023 (49.5)
|
1923 (45.2)
|
2132 (44.1)
|
5152 (48.1)
|
6133 (50.6)
|
5216 (51.2)
|
3222 (52.2)
|
2245 (51.8)
| |
|
Former
|
1728 (3.3)
|
116 (2.7)
|
189 (3.9)
|
355 (3.3)
|
410 (3.4)
|
318 (3.1)
|
213 (3.5)
|
127 (2.9)
| |
|
Never
|
8658 (16.5)
|
712 (16.7)
|
788 (16.3)
|
1700 (15.9)
|
1920 (15.9)
|
1659 (16.3)
|
1070 (17.3)
|
809 (18.7)
| |
|
Missing
|
16,210 (30.8)
|
1508 (35.4)
|
1728 (35.7)
|
3498 (32.7)
|
3649 (30.1)
|
3004 (29.5)
|
1672 (27.1)
|
1151 (26.6)
| |
|
BMI status (%)
|
|
Normal (18.5–24.9 kg/m2)
|
12,506 (23.8)
|
1052 (24.7)
|
1327 (27.4)
|
2786 (26.0)
|
2922 (24.1)
|
2350 (23.1)
|
1299 (21.0)
|
770 (17.8)
| |
|
Overweight (25.0–29.9 kg/m2)
|
14,897 (28.3)
|
1080 (25.4)
|
1229 (25.4)
|
2879 (26.9)
|
3408 (28.1)
|
3062 (30.0)
|
1933 (31.3)
|
1306 (30.2)
| |
|
Obese (≥ 30.0 kg/m2)
|
11,131 (21.2)
|
715 (16.8)
|
670 (13.9)
|
1748 (16.3)
|
2410 (19.9)
|
2382 (23.4)
|
1727 (28.0)
|
1479 (34.1)
| |
|
Underweight (< 18.5 kg/m2)
|
1075 (2.0)
|
109 (2.6)
|
182 (3.8)
|
268 (2.5)
|
272 (2.3)
|
151 (1.5)
|
58 (0.9)
|
35 (0.8)
| |
|
Missing
|
13,010 (24.7)
|
1303 (30.6)
|
1429 (29.5)
|
3024 (28.3)
|
3100 (25.6)
|
2252 (22.1)
|
1160 (18.8)
|
742 (17.1)
| |
|
BP status (%)
|
|
Normal (BP < 140/90 mmHg)
|
21,263 (40.4)
|
1608 (37.8)
|
2191 (45.3)
|
4537 (42.4)
|
4780 (39.5)
|
3966 (38.9)
|
2432 (39.4)
|
1749 (40.4)
| |
|
Stage 1 hypertension (BP ≥ 140/90 mmHg)
|
15,626 (29.7)
|
1066 (25.0)
|
1221 (25.2)
|
2841 (26.5)
|
3658 (30.2)
|
3293 (32.3)
|
2109 (34.1)
|
1438 (33.2)
| |
|
Stage 2 hypertension (BP ≥ 160/100 mmHg)
|
5166 (9.8)
|
355 (8.3)
|
332 (6.9)
|
766 (7.2)
|
1198 (9.9)
|
1184 (11.6)
|
765 (12.4)
|
566 (13.1)
| |
|
Stage 3 hypertension (systolic BP ≥ 180 mmHg or diastolic BP ≥ 110 mmHg)
|
2413 (4.6)
|
154 (3.6)
|
129 (2.7)
|
284 (2.7)
|
508 (4.2)
|
578 (5.7)
|
406 (6.6)
|
354 (8.2)
| |
|
Missing
|
8078 (15.4)
|
1070 (25.1)
|
958 (19.8)
|
2263 (21.1)
|
1953 (16.1)
|
1159 (11.4)
|
454 (7.4)
|
221 (5.1)
| |
|
TC status (%)
|
|
Optimal (< 5.2 mmol/L)
|
16,562 (31.5)
|
995 (23.4)
|
1092 (22.6)
|
2648 (24.7)
|
3560 (29.4)
|
3636 (35.7)
|
2571 (41.6)
|
2060 (47.6)
| |
|
Intermediate (5.3–6.2 mmol/L)
|
7898 (15.0)
|
519 (12.2)
|
626 (12.9)
|
1596 (14.9)
|
1929 (15.9)
|
1598 (15.7)
|
974 (15.8)
|
656 (15.1)
| |
|
High (> 6.2 mmol/L)
|
4510 (8.6)
|
314 (7.4)
|
386 (8.0)
|
921 (8.6)
|
1111 (9.2)
|
902 (8.9)
|
551 (8.9)
|
325 (7.5)
| |
|
Missing
|
23,649 (44.9)
|
2431 (57.1)
|
2733 (56.5)
|
5540 (51.8)
|
5512 (45.5)
|
4061 (39.8)
|
2081 (33.7)
|
1291 (29.8)
| |
|
Townsend score (%)
|
|
1 (least deprived)
|
10,959 (20.8)
|
809 (19.0)
|
1037 (21.4)
|
2256 (21.1)
|
2627 (21.7)
|
2155 (21.1)
|
1248 (20.2)
|
827 (19.1)
| |
|
2
|
10,833 (20.6)
|
851 (20.0)
|
1058 (21.9)
|
2216 (20.7)
|
2496 (20.6)
|
2083 (20.4)
|
1306 (21.1)
|
823 (19.0)
| |
|
3
|
9949 (18.9)
|
827 (19.4)
|
952 (19.7)
|
2051 (19.2)
|
2168 (17.9)
|
1932 (19.0)
|
1173 (19.0)
|
846 (19.5)
| |
|
4
|
8613 (16.4)
|
745 (17.5)
|
734 (15.2)
|
1716 (16.0)
|
2011 (16.6)
|
1639 (16.1)
|
1004 (16.3)
|
764 (17.6)
| |
|
5 (most deprived)
|
5995 (11.4)
|
494 (11.6)
|
515 (10.7)
|
1255 (11.7)
|
1400 (11.6)
|
1113 (10.9)
|
724 (11.7)
|
494 (11.4)
| |
|
Missing
|
6270 (11.9)
|
533 (12.5)
|
541 (11.2)
|
1211 (11.3)
|
1410 (11.6)
|
1275 (12.5)
|
722 (11.7)
|
578 (13.3)
| |
|
History of PCI (%)
|
262 (0.5)
|
13 (0.3)
|
6 (0.1)
|
26 (0.2)
|
42 (0.4)
|
51 (0.5)
|
43 (0.7)
|
81 (1.9)
| |
|
Comorbidity (%)
|
|
Hypertension
|
29,382 (55.8)
|
1802 (42.3)
|
1604 (33.2)
|
3547 (33.1)
|
6353 (52.5)
|
7208 (70.7)
|
5058 (81.9)
|
3810 (88.0)
|
< 0.01
|
|
Hyperlipidaemia
|
7510 (14.3)
|
433 (10.2)
|
463 (9.6)
|
1257 (11.7)
|
1644 (13.6)
|
1629 (16.0)
|
1187 (19.2)
|
897 (20.7)
|
< 0.01
|
|
Arrhythmia
|
8159 (15.5)
|
645 (15.1)
|
449 (9.3)
|
1095 (10.2)
|
1611 (13.3)
|
1851 (18.2)
|
1331 (21.6)
|
1177 (27.2)
|
< 0.01
|
|
Heart failure
|
2235 (4.3)
|
154 (3.6)
|
98 (2.0)
|
233 (2.2)
|
373 (3.1)
|
446 (4.4)
|
415 (6.7)
|
516 (11.9)
|
< 0.01
|
|
PVD
|
2752 (5.2)
|
209 (4.9)
|
178 (3.7)
|
450 (4.2)
|
557 (4.6)
|
583 (5.7)
|
427 (6.9)
|
348 (8.0)
|
< 0.01
|
|
Diabetes
|
8921 (17.0)
|
568 (13.3)
|
511 (10.6)
|
1313 (12.3)
|
1845 (15.2)
|
1933 (19.0)
|
1442 (23.3)
|
1309 (30.2)
|
< 0.01
|
|
Dementia
|
2549 (4.8)
|
271 (6.4)
|
518 (10.7)
|
653 (6.1)
|
518 (4.3)
|
324 (3.2)
|
170 (2.8)
|
95 (2.2)
|
< 0.01
|
|
COPD
|
4424 (8.4)
|
297 (7.0)
|
412 (8.5)
|
881 (8.2)
|
1058 (8.7)
|
892 (8.8)
|
517 (8.4)
|
367 (8.5)
|
0.02
|
|
Asthma
|
6888 (13.1)
|
494 (11.6)
|
679 (14.0)
|
1418 (13.3)
|
1642 (13.6)
|
1292 (12.7)
|
789 (12.8)
|
574 (13.3)
|
< 0.01
|
|
Liver disease
|
338 (0.6)
|
45 (1.1)
|
45 (0.9)
|
59 (0.6)
|
79 (0.7)
|
61 (0.6)
|
29 (0.5)
|
20 (0.5)
|
< 0.01
|
|
Peptic ulcer disease
|
2974 (5.7)
|
240 (5.6)
|
282 (5.8)
|
594 (5.6)
|
689 (5.7)
|
587 (5.8)
|
346 (5.6)
|
236 (5.5)
|
0.98
|
|
RA
|
1094 (2.1)
|
96 (2.3)
|
113 (2.3)
|
199 (1.9)
|
259 (2.1)
|
206 (2.0)
|
132 (2.1)
|
89 (2.1)
|
0.51
|
|
CKD
|
9366 (17.8)
|
666 (15.6)
|
597 (12.4)
|
1346 (12.7)
|
1922 (16.0)
|
2045 (20.1)
|
1495 (24.2)
|
1259 (29.2)
|
< 0.01
|
