Table 2 Associations of the FI-64 and chronic disease clusters with 10-year all-cause mortality

1. Frailty index *100 (range 1–100)

1.05

[1.05–1.06]

< .001

1.05

[1.05–1.06]

< .001

2. Frailty (yes/no)

2.20

[1.96–2.48]

< .001

2.02

[1.75–2.31]

< .001

3. Multimorbidity (range 0–10)

1.17

[1.12–1.21]

< .001

1.14

[1.10–1.19]

< .001

4. Psychiatric disorders

1.18

[1.06–1.33]

.004

1.10

[0.97–1.24]

.137

5. Musculoskeletal diseases

0.95

[0.86–1.05]

.331

1.01

[0.89–1.12]

.889

6. Brain diseases

0.97

[0.85–1.10]

.598

0.99

[0.87–1.13]

.915

7. Lung disease

1.27

[1.12–1.44]

< .001

1.20

[1.03–1.38]

.016

8. Heart disease

1.24

[1.12–1.38]

< .001

1.16

[1.02–1.32]

.022

9. Endocrine disease

1.24

[1.09–1.42]

.002

1.10

[0.93–1.29]

.283

10. Gastrointestinal diseases

1.17

[0.91–1.51]

.220

1.26

[0.94–1.60]

.126

11. Cancer

1.95

[1.73–2.18]

< .001

2.25

[1.98–2.57]

< .001

12. Cerebrovascular disease

1.65

[1.33–2.04]

< .001

1.65

[1.33–2.04]

< .001

13. Kidney disease

1.91

[1.32–2.78]

.001

1.46

[1.11–1.93]

.008

• Frailty index *100

1.05

[1.05–1.06]

< .001

1.05

[1.04–1.06]

< .001

• Multimorbidity

0.99

[0.95–1.03]

.568

1.00

[0.95–1.05]

.876

• Frailty (yes/no)

2.01

[1.76–2.29]

< .001

1.84

[1.56–2.17]

< .001

• Psychiatric disorders

1.08

[0.96–1.21]

.209

0.99

[0.87–1.13]

.897

• Musculoskeletal diseases

0.84

[0.75–0.93]

.001

0.88

[0.78–0.99]

.033

• Brain diseases

0.92

[0.81–1.04]

.198

0.94

[0.82–1.07]

.358

• Lung disease

1.13

[0.99–1.28]

.069

1.09

[0.94–1.26]

.267

• Heart disease

1.08

[0.97–1.21]

.162

1.04

[0.91–1.19]

.549

• Endocrine disease

1.04

[0.91–1.20]

.554

0.99

[0.84–1.18]

.993

• Gastrointestinal diseases

1.10

[0.85–1.41]

.481

1.13

[0.86–1.48]

.375

• Cancer

1.84

[1.64–2.06]

< .001

2.16

[1.89–2.47]

< .001

• Cerebrovascular disease

1.34

[1.07–1.66]

.009

1.25

[0.94–1.66]

.124

• Kidney disease

1.59

[1.10–2.32]

.015

1.79

[1.21–2.65]

.003