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Table 4 Adjusted association of components of the CVHI metric with common CIMT in the AWI-Gen population stratified by sex

From: Poor cardiovascular health is associated with subclinical atherosclerosis in apparently healthy sub-Saharan African populations: an H3Africa AWI-Gen study

CVHI metrics

All countries

Women

Men

 

Levels

β [95%CI]

p value

β [95% CI]

p value

β[95% CI]

p value

Smoking

Poor

Ref

Ref

Ref

Ref

Ref

Ref

Intermediate

− 1.01 [− 13.7, 11.7]

0.083

− 11.4 [− 23.9, 1.15]

< 0.001

1.41 [− 12.9, 15.7]

0.658

Ideal

3.28 [− 0.09, 7.35]

 

− 7.04 [− 10.1, − 3.98]

 

3.83 [− 16.7, 9.04]

 

Physical activity

Poor

Ref

Ref

Ref

Ref

Ref

Ref

Intermediate

− 17.5 [− 34.9, − 0.08]

0.078

− 19.8 [− 34.0, − 5.59]

< 0.001

− 10.8 [− 34.2, 12.6]

0.365

Ideal

− 12.8 [− 24.8,-0,78]

 

− 9.28 [− 14.1, − 4.51]

 

− 12.63 [− 30.4, 5.14]

 

Diet

Poor

Ref

Ref

Ref

Ref

Ref

Ref

Intermediate

1.92 [− 4.24, 8.09]

0.169

5.68 [− 1.91, 13.3]

0.059

− 2.47 [− 13.3, 8.33]

0.654

Ideal

6.75 [− 0.24, 13.7]

 

7.55 [− 1.08, 16.2]

 

6.11 [0.32, 11.9]

 

Body mass index

Poor

Ref

Ref

Ref

Ref

Ref

Ref

Intermediate

− 4.06 [− 17.4, − 2.96]

< 0.001

− 13.2 [− 25.5, − 0.94]

< 0.001

2.57 [− 20.4, 25.6]

< 0.001

Ideal

− 28.2 [− 44.2, − 12.2]

 

− 33.6 [− 50.6, − 16.6]

 

− 32.7 [− 55.1, − 10.4]

 

Hypertension

Poor

Ref

Ref

Ref

Ref

Ref

Ref

Intermediate

− 17.7 [− 26.0, − 9.28]

< 0.001

− 7.30 [− 20.4, − 5.75]

< 0.001

− 23.8 [− 27.0, − 20.6]

< 0.001

Ideal

− 31.4 [− 42.4, − 20.3]

 

− 20.2 [− 39.1, − 1.28]

 

− 28.9 [− 38.1, − 19.7]

 

Fasting glucose

Poor

Ref

Ref

Ref

Ref

Ref

Ref

Intermediate

− 18.2 [− 35.8, − 0.68]

< 0.001

− 23.3 [− 36.8, − 9.86]

< 0.001

−8.79 [− 38.7, 21.1]

0.377

Ideal

− 14.2 [− 32.8, − 4.42]

 

− 21.8 [− 35.2, − 8.27]

 

− 0.57 [− 29.1, 27.9]

 

Total cholesterol

Poor

Ref

Ref

Ref

Ref

Ref

Ref

Intermediate

− 1.89 [− 28.3, 24.5]

0.958

5.45 [− 15.1, 25.9]

0.542

− 15.8 [− 43.3, 11.6]

0.265

Ideal

− 0.58 [− 28.6, 27.5]

 

10.53 [− 11.2, 32.2]

 

− 17.8 [− 41.9, 6.21]

 
  1. Adjusted for age, sex, educational status, and socio-economic status adjusted for in the combined population while age, educational status, and socio-economic status adjusted for in the sex stratified analyses. Effect is represented by β-coefficients and is a change in mean CIMT (in μm) with each unit increase in the CVHI components. CVHI cardiovascular heath index