Fig. 2

Percentage of FASSTT Offspring participants at 3, 7 and 11 years achieving above average cognitive performance by treatment allocation of the mother during pregnancy. In children at 3 years, cognitive performance was assessed by the BSITD-III test, at 7 years by the WPPSI-III test and at 11 years by the WISC-IV test. Values are percentage of children at 3, 7 or 11 years, by treatment group of the mother, who achieved above the median cognitive score for children at that age (relative to those who scored at and below the median score); median scores are 10.0 in the BSITD-III test, 23.0 in the WPPSI-III test and 102.5 in the WISC-IV test. Total participants numbers at each age are 3 years, n = 39; 7 years, n = 70; and 11 years, n = 68. 71.4% of the children from FA-treated mothers who had cognitive scores above the median at 11 years also scored above the median at 7 years and Full Scale IQ scores at these time points were significantly correlated (r = 0.463; p < 0.0001)