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Table 2 Results of linear regression analyses for neuropsychological tests and atrophy score

From: Serum neurofilament light and tau as prognostic markers for all-cause mortality in the elderly general population—an analysis from the MEMO study

 

β per SD (95% CI)

p value

Partial η2

Memory score

 Serum NfL

− 0.27 (− 0.56–0.02)

0.067

0.0096

 Serum tau

0.10 (− 0.17–0.37)

0.46

0.0016

Speed score

 Serum NfL

− 0.41 (− 0.74–0.08)

0.014

0.017

 Serum tau

0.04 (−0.27–0.35)

0.8

0.00018

Motor score

 Serum NfL

− 0.46 (− 0.70–0.21)

< 0.001

0.036

 Serum tau

0.01 (− 0.22–0.25)

0.92

0.000031

CASCADE score

 Serum NfL

− 1.15 (− 1.83–0.47)

< 0.001

0.031

 Serum tau

0.14 (− 0.50–0.78)

0.66

0.00056

Atrophy score

 Serum NfL

0.34 (0.05–0.64)

0.023

0.02

 Serum tau

0.17 (− 0.13–0.47)

0.27

0.0048

Subcortical atrophy at the level of the anterior ventricular horns

 Serum NfL

0.001 (− 0.004–0.006)

0.64

0.00084

 Serum tau

0.005 (0.00002–0.009)

0.049

0.015

  1. All analyses were adjusted for age, sex, education, and any comorbidities. Partial η2 ≥ 0.01: small effect size. Partial η2 ≥ 0.06: medium effect size. Partial η2 ≥ 0.14: strong effect size