Table 4 Diagnostic accuracy of the BDST and the MMSE (95% confidence intervals in parentheses). SEN sensitivity, SPE specificity, AUC area under the curve, Demmo moderate dementia, Demmi mild dementia, Demmi_alz mild dementia Alzheimer’s disease, Demmi_other mild dementia, other types than Alzheimer’s disease, BDST Bamberg Dementia Screening Test, BDSTs Bamberg Dementia Screening Test, short form (sum score for the first and second subtest), BDSTus Bamberg Dementia Screening Test, ultra-short form (only score for the first subtest), MMST Mini-Mental State Examination. (1) Following the German Guideline for dementia, the MMSE scores were considered to distinguish between mild and moderate forms of dementia. Therefore, no measures of diagnostic accuracy can be presented for the MMSE and moderate dementia
Demmo vs. CNT | Demmi vs. CNT | Demmi_alz vs. CNT | Demmi_other vs. CNT | Demmi or Demmo vs. CNT | ||
|---|---|---|---|---|---|---|
MMSE | Cut-off | (1) | ≤ 26/30 | ≤ 26/30 | ≤ 26/30 | ≤ 26/30 |
SEN | .76 (.73–.79) | .79 (.76–.83) | .72 (.67–.76) | .81 (.79–.83) | ||
SPE | .88 (.82–.93) | .88 (.82–.93) | .88 (.82–.93) | .88 (.82–.93) | ||
NPV | .36 (.31–.41) | .52 (.46–.59) | .54 (.47–.60) | .35 (.30–.40) | ||
PPV | .98 (.96–.99) | .96 (.94–.98) | .94 (.91–.97) | .98 (.97–.99) | ||
AUC | .88 (.86–.91) | .90 (.88–.92) | .86 (.83–.88) | .91 (.89–.93) | ||
BDST | Cut-off | ≤ 31/50 | ≤ 37/50 | ≤ 37/50 | ≤ 37/50 | ≤ 37/50 |
SEN | 1.000 | .93 (.91–.94) | .94 (.92–.96) | .91 (.88–.94) | .94 (.93–.95) | |
SPE | 1.000 | .82 (.75–.88) | .82 (.75–.88) | .82 (.75–.88) | .82 (.75–.88) | |
NPV | .63 (.56–.70) | .77 (.70–.84) | .77 (.70–.84) | .62 (.54–.69) | ||
PPV | .97 (.96–.98) | .95 (.93–.97) | .93 (.90–.96) | .98 (.97–.99) | ||
AUC | 1.000 | .95 (.94–.97) | .96 (.95–.97) | .94 (.92–.96) | .96 (.95–.97) | |
BDSTs | Cut-off | ≤ 15/18 | ≤ 16/18 | ≤ 16/18 | ≤ 16/18 | ≤ 16/18 |
SEN | .94 (.91–.96) | .84 (.81–.86) | .87 (.85–.90) | .79 (.75–.83) | .86 (.84–.88) | |
SPE | .93 (.89–.97) | .70 (.62–.77) | .70 (.62–.77) | .70 (.62–.77) | .70 (.62–.77) | |
NPV | .88 (.82–.93) | .40 (.34–.46) | .59 (.52–.67) | .55 (.48–.62) | .26 (.22–.30) | |
PPV | .97 (.94–.99) | .95 (.93–.96) | .92 (.89–.94) | .87 (.84–.91) | .99 (.98–.99) | |
AUC | .97 (.95–.98) | .86 (.83–.88) | .89 (.86–.91) | .81 (.78–.85) | .88 (.86–.90) | |
BDSTus | Cut-off | ≤ 9/10 | – | – | – | ≤ 9/10 |
SEN | .85 (.81–.89) | .58 (.55–.61) | ||||
SPE | .86 (.81–.92) | .85 (.79–.91) | ||||
NPV | .74 (.67–.81) | .20 (.16–.23) | ||||
PPV | .93 (.89–.96) | .97 (.96–.98) | ||||
AUC | .90 (.87–.93) | .73 (.70–.77) |