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Table 1 Characteristics of ALSPAC G1 offspring and G0 parents eligible for analyses

From: Sex differences in systemic metabolites at four life stages: cohort study with repeated metabolomics

  

G1 offspring

  

G0 parents

 
 

Males

 

Females

 

Males

 

Females

Characteristics

N

 

N

 

N

 

N

 

Age (years) on first clinic occasion—mean (SD)

3410

7.5 (0.3)

3376

7.5 (0.3)

1855

53.2 (5.3)

4645

47.9 (4.5)

Non-white ethnicity—% (N)

3328

< 5.0 (NA*)

3422

< 5.0 (NA*)

4175

< 5.0 (NA*)

4219

< 5.0 (NA*)

Highest maternal education—% (N)

3389

 

3470

 

 

4233

 

 Certificate of secondary education

 

13.3 (450)

 

14.0 (484)

 

 

10.2 (430)

 Vocational

 

8.4 (286)

 

8.4 (293)

 

 

7.4 (313)

 Ordinary level

 

35.7 (1209)

 

34.2 (1185)

 

 

34.3 (1453)

 Advanced level

 

26.3 (891)

 

26.9 (932)

 

 

29.3 (1238)

 Degree

 

16.3 (553)

 

16.6 (576)

 

 

18.9 (799)

Highest partner education—% (N)

3293

 

3378

 

4142

 

 

 Certificate of secondary education

 

19.0 (625)

 

21.5 (725)

 

16.9 (699)

 

 Vocational

 

7.6 (251)

 

7.7 (259)

 

7.4 (308)

 

 Ordinary level

 

22.3 (734)

 

21.4 (723)

 

21.0 (869)

 

 Advanced level

 

28.1 (925)

 

27.4 (926)

 

29.3 (1213)

 

 Degree

 

23.0 (758)

 

22.1 (745)

 

25.4 (1053)

 

BMI on first clinic occasion—mean (SD)

3385

16.1 (1.9)

3350

16.4 (2.2)

1831

27.5 (4.0)

4629

26.6 (5.3)

Maternal BMI pre-pregnancy—mean (SD)

3163

22.9 (3.8)

3246

22.8 (3.6)

3991

22.5 (3.4)

Partner BMI at pregnancy—mean (SD)

2438

25.1 (3.1)

2544

25.2 (3.3)

1493

24.7 (3.0)

Maternal smoking during pregnancy—% (N)

3133

22.5 (706)

3181

22.4 (713)

3919

17.0 (665)

Partner smoking during pregnancy—% (N)

3271

29.7 (972)

3333

31.6 (1054)

4070

27.3 (1112)

 

Age (y) at peak height velocity—mean (SD)

2404

13.6 (0.9)

2688

11.7 (0.8)

Menopause status (STRAW)—% (N)

3513

 

 Pre-menopause

 

 

 

 

62.1 (2181)

 Peri-menopause

 

 

 

 

19.4 (680)

 Post-menopause

 

 

 

 

18.6 (652)

  1. Participants described are those with data on sex, age, and at least 1 metabolite on any measurement occasion. ‘Maternal/partner’ characteristics refer to own status among parents. BMI body mass index. STRAW Stages of Reproductive Age Workshop. *Cells have been censored due to small cell counts in accordance with study ethics