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Table 2 COVID-19 infections missed per 10,000 population tested, with and without pooling, under varied testing capacity, pooling and test sensitivity

From: Exit strategies: optimising feasible surveillance for detection, elimination, and ongoing prevention of COVID-19 community transmission

Row

Prevalence of COVID-19 in those being tested

Number with disease per 10,000

Sensitivity of pooled test

Exhaustive testing of 10,000 individuals using 1/4 pooling

Exhaustive testing of 10,000 individuals using 1/16 pooling

Percentage cases missed with no pooling (test sensitivity of 99.9%)

Col 1

Col 2

Col 3

Col 4

Same number of tests used and individuals tested as in column 1

Same number of tests used and individuals tested as in column 3

Total tests needed

Percentage of cases missed

Total tests needed

Percentage of cases missed

1

0.05%

5

99.90%

2530

0%

715

1%

75%

93%

2

0.05%

5

95.00%

2529

5%

711

5%

75%

93%

3

0.05%

5

90.00%

2528

10%

707

10%

75%

93%

4

0.05%

5

80.00%

2526

20%

699

20%

75%

93%

5

0.05%

5

70.00%

2524

30%

691

30%

75%

93%

6

0.10%

10

99.90%

2550

0%

793

1%

75%

92%

7

0.10%

10

95.00%

2548

5%

786

6%

75%

92%

8

0.10%

10

90.00%

2546

10%

778

11%

75%

92%

9

0.10%

10

80.00%

2542

20%

762

21%

75%

92%

10

0.10%

10

70.00%

2538

30%

746

31%

75%

93%

11

1.00%

100

99.90%

2903

2%

2117

7%

71%

79%

12

1.00%

100

95.00%

2884

7%

2045

12%

71%

80%

13

1.00%

100

90.00%

2864

11%

1970

17%

71%

80%

14

1.00%

100

80.00%

2825

21%

1822

26%

72%

82%

15

1.00%

100

70.00%

2785

31%

1673

35%

72%

83%

16

3.00%

300

99.90%

3655

5%

4485

20%

63%

55%

17

3.00%

300

95.00%

3599

9%

4296

24%

64%

57%

18

3.00%

300

90.00%

3541

14%

4103

28%

65%

59%

19

3.00%

300

80.00%

3427

24%

3717

36%

66%

63%

20

3.00%

300

70.00%

3312

33%

3331

44%

67%

67%

  1. Test specificity 99.9% for all scenarios