Fig. 2

Cox proportional hazards regression, adjusted by age and gender, albuminuria and eGFR categories, and multiple confounders, according to eGDR tertiles, in participants with no DKD (a), albuminuric DKD with preserved eGFR (b), nonalbuminuric DKD (c) and albuminuric DKD with reduced eGFR (d). HRs (95% CI) for mortality are shown for each tertile. CVD risk factors (smoking habits, diabetes duration, and dyslipidaemia) and complications/comorbidities (DR grade, prior CVD, and cancer). eGFR, estimated glomerular filtration rate; eGDR, estimated glucose disposal rate; DKD, diabetic kidney disease; HR, hazard ratio; CI, confidence interval; CVD, cardiovascular disease; DR, diabetic retinopathy