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Table 2 The estimate changes of national labour neuraxial analgesia rates (%) after the national policy

From: The trends and associated adverse maternal and perinatal outcomes of labour neuraxial analgesia among vaginal deliveries in China between 2012 and 2019: a real-world observational evidence

Variables Crude model a Adjusted model a, b
β (coefficient) P value 95% CI β (coefficient) P value 95% CI
Lower Upper Lower Upper
Single-group (all hospitals) Maximum lag: 4 Maximum lag: 4
 Baseline intercept (β0) 7.61 < 0.001 7.02 8.19 23.85 0.001 10.02 37.68
 Baseline slope (β1) 0.04 < 0.001 0.02 0.06 0.15 0.010 0.03 0.26
 Intercept change (post-intervention) (β2) 2.77 < 0.001 1.39 4.15 1.35 0.101 − 0.27 2.96
 Slope change (post-intervention) (β3) 0.48 < 0.001 0.41 0.56 0.46 < 0.001 0.33 0.59
Single-group (pilot hospitals) Maximum lag: 5 Maximum lag: 4
 Baseline intercept (β0) 12.82 < 0.001 11.85 13.80 24.73 0.011 5.72 43.75
 Baseline slope (β1) 0.03 0.029 0.00 0.06 0.14 0.055 0.00 0.27
 Intercept change (post-intervention) (β2) 2.65 0.005 0.83 4.46 1.54 0.129 − 0.46 3.54
 Slope change (post-intervention) (β3) 0.63 < 0.001 0.53 0.72 0.67 < 0.001 0.50 0.84
Multiple-group (Pilot and non-pilot hospitals) Maximum lag: 6 Maximum lag: 5
 Baseline intercept of non-pilot hospitals (β0) 4.64 < 0.001 4.24 5.05 9.36 0.039 0.48 18.23
 Baseline slope of non-pilot hospitals (β1) 0.03 < 0.001 0.01 0.05 0.10 0.056 0.00 0.21
 Intercept change of non-pilot hospitals (post-intervention) (β2) 2.47 < 0.001 1.36 3.58 2.16 < 0.001 1.02 3.30
 Slope change of non-pilot hospitals (post-intervention) (β3) 0.38 < 0.001 0.34 0.42 0.40 < 0.001 0.30 0.49
 Difference of the intercept between pilot and non-pilot hospitals (prior-intervention) (β4) 8.18 < 0.001 7.1 9.26 13.01 < 0.001 6.58 19.44
 Difference of the slope between pilot and non-pilot hospitals (prior-intervention) (β5) 0.00 0.899 − 0.03 0.03 −0.01 0.578 − 0.04 0.02
 Difference of the change of intercept immediately following intervention between pilot and non-pilot hospitals (β6) 0.18 0.874 − 2.02 2.38 −0.28 0.808 − 2.53 1.98
 Difference of the slope between pilot and non-pilot hospitals (post-intervention versus prior-intervention) (β7) 0.25 < 0.001 0.15 0.35 0.23 0.001 0.09 0.37
  1. CI confidence interval
  2. aThe model is estimated using Newey-West standard errors to handle autocorrelation
  3. bThe model is adjusted for the proportion of maternal age ≥ 35 years old, women with college education or above, number of antenatal visits ≥ 7 and women with antepartum complications or medical diseases
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BMC Medicine

ISSN: 1741-7015

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