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Fig. 3 | BMC Medicine

Fig. 3

From: Quantifying the potential value of antigen-detection rapid diagnostic tests for COVID-19: a modelling analysis

Fig. 3

Relative value of Ag-RDT vs NAT testing, for averting infections in a hospital setting. a Scatter plots for the relative impact of Ag-RDT vs NAT (horizontal axis) vs the relative cost of the two strategies (vertical axis). Of the yellow points (no NAT confirmation of Ag-RDT results), 27% fell in the favourable region shaded in grey. Details as in Fig. 2a and Additional file 3: Fig.S1. b Sensitivity analysis for model parameters on the yellow points in a. The interpretation of PRCC is explained in further detail in the caption of Fig. 2. c concentrates on the two most influential parameters in this case, NAT availability and sensitivity of clinical judgement. As in Fig. 2c, grey and black points show parameter regimes where an Ag-RDT was, respectively, favourable and unfavourable, relative to NAT. Red lines show 80% sensitivity of clinical judgement (vertical line) and 65% NAT availability (horizontal line). In the lower left quadrant of these lines, an Ag-RDT was favourable over NAT in 66% of simulations. In these results, it was assumed that patients were placed in isolation while awaiting a NAT result: Additional file 6: Fig.S3 in the supporting information shows results in the alternative scenario where they were not isolated

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