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Table 2 Associations between age at peak height velocity and cardiac structure and function in males and females at age 25

From: Puberty timing and markers of cardiovascular structure and function at 25 years: a prospective cohort study

  Males Females
Outcome Crude estimate (95% CI)a Adjusted estimate (95% CI)a,b Crude estimate (95% CI)a Adjusted estimate (95% CI)a,b
CIMT 0.0001 (− 0.002, 0.003) 0.003 (0.00001, 0.006) − 0.0007 (− 0.003, 0.002) 0.0008 (− 0.002, 0.003)
LVMI − 1.00 (− 0.50, − 1.50) − 0.55 (− 0.03, − 1.08) − 1.17 (− 0.74, − 1.59) − 0.89 (− 0.45, −1.34)
RWT − 0.003 (− 0.007, 0.0009) − 0.001 (− 0.006, 0.002) − 0.002 (− 0.006, 0.001) − 0.002 (− 0.006, 0.002)
PWV − 0.04 (− 0.11, 0.02) 0.02 (− 0.05, 0.09) − 0.03 (− 0.09, 0.01) 0.02 (− 0.04, 0.09)
SBP − 0.97 (− 0.40, − 1.54) 0.003 (− 0.60, 0.60) − 1.20 (− 0.69, − 1.71) 0.13 (− 0.44, 0.70)
  1. aPHV age at peak height velocity, CI confidence interval, CIMT carotid intima-media thickness, LVMI left ventricular mass index, RWT relative wall thickness, PWV pulse wave velocity, SBP systolic blood pressure
  2. aAssociation of a one-year older aPHV with each outcome
  3. bAdjusted for maternal age, gestational age, household social class, maternal education, mother’s partner’s education, breastfeeding of baby until 3 months, parity, birthweight, maternal body mass index, maternal marital status, maternal smoking status during first 3 months of pregnancy, and height and fat mass of offspring at age 9