From: Using Mendelian randomization study to assess the renal effects of antihypertensive drugs
Class | #SNPs | Odds ratio | 95% CI | p |
---|---|---|---|---|
CCBs | 8 | 0.58 | 0.37, 0.90 | 0.01 |
Alpha-adrenoceptor blockers | 6 | 0.81 | 0.41, 1.60 | 0.54 |
Adrenergic neuron blockers | 3 | 1.45 | 0.56, 3.75 | 0.44 |
Beta-adrenoceptor blockers | 7 | 0.71 | 0.35, 1.46 | 0.35 |
Centrally acting antihypertensives | 4 | 0.54 | 0.21, 1.39 | 0.20 |
Loop diuretics | 2 | 1.39 | 0.43, 4.52 | 0.58 |
PSDs and aldosterone antagonists | 3 | 1.17 | 0.41, 3.37 | 0.77 |
Thiazides and related diuretics | 4 | 0.81 | 0.31, 2.11 | 0.66 |
Vasodilator antihypertensives | 8 | 1.04 | 0.51, 2.14 | 0.92 |