TY - JOUR AU - Huang, Wen AU - Zhou, Jin AU - Guo, Juanjuan AU - Hu, Wen AU - Chen, Guanghui AU - Li, Bin AU - Wen, Yajie AU - Jiang, Yimin AU - Fu, Kaili AU - Bi, Huichang AU - Zhang, Yuanzhen AU - Wang, Hui PY - 2021 DA - 2021/04/07 TI - Dexamethasone induces an imbalanced fetal-placental-maternal bile acid circulation: involvement of placental transporters JO - BMC Medicine SP - 87 VL - 19 IS - 1 AB - The use of prenatal dexamethasone remains controversial. Our recent studies found that prenatal dexamethasone exposure can induce maternal intrahepatic cholestasis and have a lasting adverse influence on bile acid (BA) metabolism in the offspring. The purpose of this study was to investigate the effects of dexamethasone on fetal-placental-maternal BA circulation during the intrauterine period, as well as its placental mechanism. SN - 1741-7015 UR - https://doi.org/10.1186/s12916-021-01957-y DO - 10.1186/s12916-021-01957-y ID - Huang2021 ER -