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Fig. 3 | BMC Medicine

Fig. 3

From: Dexamethasone induces an imbalanced fetal-placental-maternal bile acid circulation: involvement of placental transporters

Fig. 3

Effects of dexamethasone on rat fetal and maternal serum bile acid metabolic profile. Bile acids’ metabolic profile of male fetal serum (a), female fetal serum (b), and maternal serum (c) were determined by liquid chromatography/mass spectrometry (LC-MS). The relative amount of bile acid was displayed as a log intensity of the peak area. Data are presented as mean ± SD, n = 11 per group. *P < 0.05 vs. control. **P < 0.01 vs. control. CA, cholic acid; CDCA, chenodeoxycholic acid; MCA, muricholic acid; TCA, taurocholic acid; TCDCA, tauro-chenodeoxycholic acid; TMCA, tauro-muricholic acid; DCA, deoxycholic acid; UDCA, ursodeoxycholic acid; HDCA, hyodeoxycholic acid; TDCA, tauro-deoxycholic acid; TUDCA, tauro-ursodeoxycholic acid; THDCA, tauro-hyodeoxycholic acid; PDE, 0.2 mg kg−1 day−1 dexamethasone

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