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Table 4 Prediction of CKD stage 3b or more severe

From: Prediction of individuals at high risk of chronic kidney disease during treatment with lithium for bipolar disorder

MODEL

ROC area (95%CI)

Sensitivity (95%CI)

Specificity (95%CI)

Accuracy, %

Development (Aurum)

 Full

0.700 (0.617–0.783)

0.71 (0.52–0.90)

0.66 (0.47–0.85)

66.12

 3-variable KFRE

0.627 (0.543–0.710)

0.68 (0.51–0.86)

0.61 (0.48–0.74)

61.18

 3-variable elastic net

0.678 (0.598–0.758)

0.58 (0.37–0.78)

0.73 (0.48–0.98)

72.64

Validation (Gold)

 Full

0.849 (0.792–0.905)

1.00 (0.96–1.00)

0.67 (0.57–0.76)

67.49

 3-variable KFRE

0.858 (0.792–0.922)

0.86 (0.70–1.00)

0.78 (0.63–0.93)

78.12

 3-variable elastic net

0.865 (0.808–0.921)

1.00 (0.92–1.00)

0.66 (0.57–0.75)

66.51