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Fig. 1 | BMC Medicine

Fig. 1

From: Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition

Fig. 1

Smile plot with associations between metabolites with BMI, WC and WHR in the discovery set. a BMI, b WC, and c WHR. Smile plot with FDR (false discovery rate method) q values. Analysis using residuals from Z and Log transformed metabolites with fixed effect for country and sex and random effect for batches nested within studies. Models were adjusted for age at blood collection, fasting status at blood collection, smoking status at recruitment, Cambridge physical activity index, height, and daily intake of energy, red and processed meat, fish and shellfish, fibre, and alcohol. The metabolites above the horizontal line showed a significant association with the anthropometric measure (p < 0.05)

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