| European Prospective Investigation into Cancer and Nutrition | Intercept* | |||||
---|---|---|---|---|---|---|---|
Discovery | Replication | Colorectal cancer | Endometrial cancer | Â | |||
 |  | Cases | Controls | Cases | Control |  | |
(n = 3029) | (n = 1297) | (n = 423) | (n = 423) | (n = 635) | (n = 648) | (n = 17) | |
Age, mean (SD) | 55.5 (8.1) | 55.8 (8.2) | 55.7 (7.8) | 55.8 (7.9) | 53.96 (7.9) | 53.99 (7.9) | 37.5 (9.7) |
Sex, n (%) | |||||||
 Women | 964 (31.8) | 431 (33.2) | 257 (60.8) | 253 (59.9) | 635 (100) | 648 (100) | 11 (64.7) |
Educational level, n (%) | |||||||
 University or higher | 674 (22.2) | 296 (22.8) | 62 (14.6) | 65 (15.3) | 116 (18.2) | 92 (14.2) | 13 (76.4) |
Body mass index (kg/m2), mean (SD) | 26.45 (3.7) | 26.47 (3.7) | 27.1 (4.5) | 26.51Â (3.6) | 28 (5.4) | 25.85 (4.2) | 34.2 (3.8) |
Categories of BMI, n (%) | |||||||
 Normal weight | 1101 (36.3) | 467 (36.0) | 142 (33.6) | 141 (33.3) | 210 (33.1) | 315 (48.6) | – |
 Overweight | 1456 (48.1) | 619 (47.7) | 182 (43.0) | 216 (51.0) | 226 (35.6) | 239 (36.8) | 1 (5.8) |
 Obese | 472 (15.6) | 211 (16.3) | 99 (23.4) | 66 (15.6) | 199 (31.3) | 94 (14.5) | 16 (94.2) |
Waist circumference (cm), mean (SD) | 90.7 (12.0) | 90.4 (12.1) | 89.6 (13.3) | 87.8 (11.5) | 85.7 (12.1) | 81.5 (10.5) | 102.8 (8.0) |
Waist-hip ratio (cm), mean (SD) | 0.89 (0.09) | 0.89 (0.09) | 0.87Â (0.09) | 0.86 (0.1) | 0.81 (0.06) | 0.80 (0.06) | 0.86 (0.7) |
Height (cm), mean (SD) | 169.0 (8.8) | 168.9 (8.9) | 164.3 (9.1) | 163.8 (9.4) | 160.2 (6.6) | 160.2 (6.8) | 170.6 (7.9) |
Physical activity, n (%) | |||||||
 Inactive | 679 (22.4) | 296 (22.8) | 133 (31.4) | 122 (28.8) | 95 (14.9) | 86 (13.3) | NA |
 Moderately inactive | 1026 (33.9) | 463 (35.7) | 183 (43.2) | 175 (41.4) | 189 (29.7) | 175 (27.0) | NA |
 Moderately active | 670 (22.1) | 278 (21.4) | 63 (14.9) | 71 (16.8) | 18 (2.8) | 13 (2.0) | NA |
 Active | 597 (19.7) | 237 (18.3) | 44 (10.4) | 54 (12.7) | 115 (18.1) | 126 (19.4) | NA |
Smoking status, n (%) | |||||||
 Never smoker | 1224 (40.4) | 518 (39.9) | 198 (46.8) | 222 (52.5) | 82 (12.9) | 111 (17.1) | NA |
 Current smoker | 703 (23.2) | 299 (23.0) | 90 (21.3) | 77 (18.2) | 417 (65.6) | 396 (61.1) | NA |
Meat intake (g/d), mean (SD) | 86.5 (55.2) | 88.9 (59.5) | 76.7 (81.7) | 77.6 (44.4) | 634.7 (378.8) | 646.2 (376.4) | NA |
Fish intake (g/d), mean (SD) | 37.1 (37.2) | 35.3 (33.7) | 36.3 (32.4) | 37.9 (36.5) | 523.9 (316.5) | 509.0 (312.9) | NA |
Fibre intake (g/d), mean (SD) | 23.7 (8.1) | 23.3 (7.8) | 22.9 (7.6) | 23.3 (8.0) | Â | Â | NA |
Alcohol intake (g/d), mean (SD) | 3.1 (1.3) | 3.1 (1.27) | 2.9 (1.4) | 2.7 (1.3) | 3.1 (1.2) | 3.1 (1.2) | NA |
Energy intake (g/d), mean (SD) | 2253 (654.7) | 2255 (643.0) | 2221 (829.0) | 2187 (627.9) | 661 (383.9) | 667 (380.1) | NA |
Fasting status, n (%) | |||||||
 Non-fasting | 1351 (44.6) | 601 (46.3) | 23 (5.4) | 23 (5.4) | 99 (15.6) | 105 (16.2) | 17 (100) |
Sub-study, n (%) | |||||||
 Breast cancer controls | 752 (24.8) | 332 (25.6) | n/a | n/a | n/a | n/a | n/a |
 Kidney cancer controls | 346 (11.4) | 134 (10.3) | n/a | n/a | n/a | n/a | n/a |
 Hepatobiliary cancer controls | 151 (4.9) | 65 (5.0) | n/a | n/a | n/a | n/a | n/a |
 Prostate cancer controls | 1780 (58.7) | 766 (59.0) | n/a | n/a | n/a | n/a | n/a |